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用于治疗毛地黄属植物中毒的抗洋地黄Fab片段

[Antidigitalis Fab-fragment for treating poisoning from a foxglove plant].

作者信息

Vibe Nielsen Sanne, Petersen Rasmus Hjelmar

机构信息

Anæstesiologisk Afdeling, Sydvestjysk Sygehus Esbjerg, Finsensgade 35, 6700 Esbjerg, Denmark.

出版信息

Ugeskr Laeger. 2013 Jun 10;175(24):1701-2.

Abstract

Plant poisonings are rare in Denmark, but can have fatal consequences. We present a case in which a woman went into cardiac arrest after having ingested leaves from the foxglove plant. Sinus rhythm was not restored until Digibind was administered. Literature in this field is sparse, but we conclude that the following advice can be given: 1) assessment of the degree of poisoning should be based on clinical features and changes of the electrocardiogram; 2) activated charcoal should be given; 3) in case of malignant arrhythmia or cardiac arrest, the use of Digibind should be considered.

摘要

植物中毒在丹麦较为罕见,但可能会导致致命后果。我们报告一例病例,一名女性在摄入毛地黄植物的叶子后心脏骤停。直到给予地高辛抗体片段后,窦性心律才得以恢复。该领域的文献较少,但我们得出结论,可以给出以下建议:1)中毒程度的评估应基于临床特征和心电图变化;2)应给予活性炭;3)如果出现恶性心律失常或心脏骤停,应考虑使用地高辛抗体片段。

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