Victorian Infant Brain Studies, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia.
Early Hum Dev. 2013 Sep;89(9):727-32. doi: 10.1016/j.earlhumdev.2013.05.005. Epub 2013 Jun 10.
Sensory profiles are increasingly used by therapists to assess children. There is limited information on how sensory profiles differ between very preterm (VPT) children and term controls, or on the predictors of sensory profiles in VPT children.
The aim of this study was to examine sensory profiles of children born <30 weeks' gestation at 2 years and their environmental and biological influences.
Cohort study.
253 VPT children born <30 weeks' gestation and 65 term-born controls (>36 weeks' gestation).
Sensory profiles were examined with the Infant/Toddler Sensory Profile Questionnaire, which measures the child's responsiveness in four sensory quadrants and in five sensory processing sections. Standardised z scores for the VPT sample were compared with the controls, and predictors of VPT infant sensory profiles were determined.
VPT children had scores consistent with stronger patterns across all four sensory quadrants compared with controls, indicating a stronger interaction between neurological thresholds to elicit a response and self-regulation strategies. In addition they also exhibited more of the behaviours in all sensory processing sections compared with controls. Male sex, higher social risk, increasing length of stay, and moderate to severe white matter abnormality on MRI at term-equivalent age were associated with stronger sensory profile patterns in some quadrants, and more behaviours in some sensory processing sections.
Sensory profiles differed between VPT children and term-born controls, with stronger sensory profile patterns associated with male sex, higher social risk, longer hospital stay, and moderate to severe white matter abnormality.
治疗师越来越多地使用感觉概况来评估儿童。关于极早产儿（VPT）儿童和足月对照儿童之间的感觉概况差异，或 VPT 儿童感觉概况的预测因素，信息有限。
本研究旨在研究<30 周出生的儿童在 2 岁时的感觉概况及其环境和生物学影响。
队列研究。
253 名出生于<30 周妊娠的 VPT 儿童和 65 名足月出生的对照儿童（>36 周妊娠）。
使用婴儿/幼儿感觉概况问卷检查感觉概况，该问卷测量儿童在四个感觉象限和五个感觉处理部分的反应性。将 VPT 样本的标准化 z 分数与对照组进行比较，并确定 VPT 婴儿感觉概况的预测因素。
VPT 儿童的感觉概况与对照组相比，所有四个感觉象限的反应模式都更强，这表明神经系统阈值引起反应和自我调节策略之间的相互作用更强。此外，与对照组相比，他们在所有感觉处理部分也表现出更多的行为。男性、更高的社会风险、住院时间延长以及在足月等效年龄时 MRI 上出现中度至重度脑白质异常与某些象限的更强感觉概况模式以及某些感觉处理部分的更多行为相关。
VPT 儿童与足月出生的对照儿童的感觉概况不同，更强的感觉概况模式与男性、更高的社会风险、住院时间延长和中度至重度脑白质异常相关。
