Dept of Pathology, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1194, New York, NY 10029, USA.
Am J Clin Pathol. 2013 Jul;140(1):103-8. doi: 10.1309/AJCP9HDXYB2WYYJX.
To identify, describe, and investigate the clinical, radiologic, and pathologic features of 8 cases of telangiectatic oncocytoma.
Fifty-three consecutive renal oncocytomas were reviewed for the telangiectatic pathologic features that were subsequently correlated with the demographic, clinical, and radiographic findings.
Telangiectatic oncocytoma accounted for 15% of the 53 renal oncocytomas collected in the past 7 years in our institution. On radiology, almost all presented as an enhancing mass and were suspicious for or consistent with a renal malignant tumor. Grossly, the tumors ranged from 2.4 to 6.0 cm (mean, 3.5 cm) and macroscopically were hemorrhagic spongy or multicystic masses without a central stellate scar. Microscopically, they were characterized by variably sized blood-distended spaces (<0.1-mm to 2- to 3-mm blood lakes) lined by typical oncocytoma cells and without evidence of degenerative changes.
With its unique radiologic and pathologic presentations in comparison with classic renal oncocytoma, it is important to recognize this new variant of renal oncocytoma.
识别、描述并研究 8 例血管扩张型嗜酸细胞瘤的临床、放射学和病理学特征。
回顾性分析 53 例连续的肾嗜酸细胞瘤中存在的血管扩张性病变特征,并将其与人口统计学、临床和影像学表现进行相关分析。
在过去 7 年中,我们医院共收集了 53 例肾嗜酸细胞瘤,其中血管扩张型嗜酸细胞瘤占 15%。影像学上,几乎所有肿瘤均为增强肿块,提示或符合肾恶性肿瘤。大体上,肿瘤大小为 2.4 至 6.0cm(平均 3.5cm),肉眼为出血海绵状或多囊性肿块,无中央星状瘢痕。镜下,肿瘤由大小不等的充满血液的腔隙(<0.1mm 至 2-3mm 的血池)组成,由典型的嗜酸细胞瘤细胞排列,无退行性改变的证据。
与经典的肾嗜酸细胞瘤相比,该肿瘤具有独特的影像学和病理学表现,因此,认识这种新型的肾嗜酸细胞瘤是很重要的。