[结肠和直肠癌肿瘤中的核DNA含量。倍性与肿瘤部位之间的关系]
[Nuclear DNA content in tumors of the colon and rectum. Relationship between ploidy and site of the neoplasm].
作者信息
Larghero G C, Ottonello M, Testa T, Scarpettini S, Abbondati A, Capponi G
机构信息
Cattedra di Patologia Speciale Chirurgica II, Università degli Studi di Genova.
出版信息
Minerva Chir. 1990 Mar 15;45(5):247-50.
The DNA distribution pattern was determined 30 colo-rectal carcinomas. The DNA content in individual cells was measured according to a cytophotometric method based on light transmission measurement of Feulgen-stained nuclei. The DNA non diploid carcinomas were significantly more common from the left (descending and sigmoid) colon and rectum (P = 0.0002). No relationship existed between DNA pattern and age, sex, Dukes' stage, tumor grade.
对30例结肠直肠癌的DNA分布模式进行了测定。根据基于福尔根染色细胞核光透射测量的细胞光度法测量单个细胞中的DNA含量。DNA非二倍体癌在左半结肠（降结肠和乙状结肠）和直肠更为常见（P = 0.0002）。DNA模式与年龄、性别、杜克分期、肿瘤分级之间无相关性。
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