University of Illinois, Department of Speech and Hearing Science, 901 6th Street, Champaign, IL 61820, USA.
J Fluency Disord. 2013 Jun;38(2):66-87. doi: 10.1016/j.jfludis.2012.11.002. Epub 2012 Nov 27.
Epidemiological advances in stuttering during the current century are reviewed within the perspectives of past knowledge. The review is organized in six sections: (a) onset, (b) incidence, (c) prevalence, (d) developmental paths, (e) genetics and (f) subtypes. It is concluded that: (1) most of the risk for stuttering onset is over by age 5, earlier than has been previously thought, with a male-to-female ratio near onset smaller than what has been thought, (2) there are indications that the lifespan incidence in the general population may be higher than the 5% commonly cited in past work, (3) the average prevalence over the lifespan may be lower than the commonly held 1%, (4) the effects of race, ethnicity, culture, bilingualism, and socioeconomic status on the incidence/prevalence of stuttering remain uncertain, (5) longitudinal, as well as incidence and prevalence studies support high levels of natural recovery from stuttering, (6) advances in biological genetic research have brought within reach the identification of candidate genes that contribute to stuttering in the population at large, (7) subtype-differentiation has attracted growing interest, with most of the accumulated evidence supporting a distinction between persistent and recovered subtypes.
Readers will be exposed to a summary presentation of the most recent data concerning basic epidemiological factors in stuttering. Most of these factors also pertain to children's risks for experiencing stuttering onset, as well as risks for persistency. The article also aims to increase awareness of the implications of the information to research, and professional preparation that meets the epidemiology of the disorder.
在当前世纪,口吃的流行病学进展在过去知识的视角下进行了回顾。该综述分为六个部分:(a)发病、(b)发病率、(c)患病率、(d)发展路径、(e)遗传学和(f)亚型。结论如下:(1)口吃发病的大部分风险在 5 岁前就已结束,比之前认为的更早,发病时的男女比例小于之前认为的,(2)有迹象表明,一般人群的终生发病率可能高于过去工作中常提到的 5%,(3)终生平均患病率可能低于普遍认为的 1%,(4)种族、民族、文化、双语和社会经济地位对口吃发病率/患病率的影响仍不确定,(5)纵向以及发病率和患病率研究均支持口吃的自然康复率很高,(6)生物遗传研究的进展使识别一般人群中导致口吃的候选基因成为可能,(7)亚型分化引起了越来越多的关注,大多数积累的证据支持将持续性和恢复性亚型区分开来。
读者将接触到有关口吃基本流行病学因素的最新数据的摘要介绍。这些因素大多也与儿童口吃发病风险以及持续性风险有关。本文还旨在提高对口吃信息对研究和满足该障碍流行病学的专业准备的认识。