Guo Min-Xia, Fu Yong-Fu
Ministry of Agriculture Key Lab of Soybean Biology, National Key Facility of Crop Gene Resource and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Yi Chuan. 2013 Jun;35(6):727-34. doi: 10.3724/sp.j.1005.2013.00727.
SUMO (Small ubiquitin-related modifier) modification, one of the essential posttranslational modifications in eukaryotes, plays an important role in various cellular processes. This review summarized the recent progresses on SUMO substrates in Arabidopsis. We firstly described the pathway of SUMO conjugation, and then focused on screening for SUMO substrates, including the methods of identification and SUMO substrates identified. Finally, we classified these substrates on the basis of their subcellular localization, functions, and biological processes. It is expected to provide the basis for better understanding the roles of sumoylation of proteins in plants.
SUMO（小泛素相关修饰物）修饰是真核生物中重要的翻译后修饰之一，在各种细胞过程中发挥着重要作用。本综述总结了拟南芥中SUMO底物的最新研究进展。我们首先描述了SUMO缀合途径，然后重点介绍了SUMO底物的筛选，包括鉴定方法和已鉴定的SUMO底物。最后，我们根据这些底物的亚细胞定位、功能和生物学过程对其进行了分类。期望为更好地理解植物中蛋白质SUMO化的作用提供依据。
