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[肌肉骨骼疾病的非药物、非技术治疗:以膝关节骨关节炎和老年人跌倒为例的临床试验方法学挑战]

[Non-pharmacological, non-technical treatments for musculoskeletal disease: methodological challenges of clinical trials using the example of knee osteoarthritis and falls in the elderly].

作者信息

Thiem Ulrich, Trampisch Ulrike, Trampisch Hans-Joachim

机构信息

Klinik für Altersmedizin und Frührehabilitation, Marienhospital Herne, Ruhr-Universität Bochum, Widumer Strasse 8, Herne.

出版信息

Z Evid Fortbild Qual Gesundhwes. 2013;107(3):230-4. doi: 10.1016/j.zefq.2013.04.002. Epub 2013 May 14.

DOI:10.1016/j.zefq.2013.04.002
PMID:23790701
Abstract

Physical therapy modalities are regarded as an integral part of the treatment of musculoskeletal diseases like osteoarthritis of the knee or falls in the elderly. Guidelines and treatment recommendations promote such interventions. However, the evidence supporting physical therapy modalities is often weaker than that found for drug treatments. One reason is that a simple blinding of treatment assignments by means of a placebo is usually not possible. Another issue is patient preferences that have an impact on the conduct of the study and the interpretation of the results. This article highlights methodological challenges of studies investigating physical therapy modalities, and points out some possible solutions. (As supplied by publisher).

摘要

物理治疗方法被视为治疗肌肉骨骼疾病(如膝关节骨关节炎或老年人跌倒)不可或缺的一部分。指南和治疗建议都提倡此类干预措施。然而,支持物理治疗方法的证据往往比药物治疗的证据更薄弱。一个原因是,通常不可能通过安慰剂对治疗分配进行简单的盲法处理。另一个问题是患者的偏好会影响研究的实施和结果的解读。本文强调了研究物理治疗方法时的方法学挑战,并指出了一些可能的解决方案。(由出版商提供)

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