Leavitt D D, Stewart J R, Earley L
Department of Radiology, University of Utah Medical Center, Salt Lake City 84132.
Int J Radiat Oncol Biol Phys. 1990 Jul;19(1):159-65. doi: 10.1016/0360-3016(90)90149-e.
Improved dose homogeneity throughout the treatment volume defined for electron arc therapy is achieved through superposition of multiple arcs of different electron energy to the same treatment surface. The relative weights for each arc segment and energy are determined by computer optimization which minimizes the variation in radial depth dose across the treatment volume. In addition to the standard electron beam energies of 6 MeV, 9 MeV, 12 MeV, 16 MeV and 20 MeV, a new electron arc field is created by adding bolus to the treatment surface during an additional pass using 6 MeV electrons. This modified field, having maximum dose on the patient surface and a reduced range, supplements the dose delivered by the standard electron arc fields in the buildup region. Through use of this multiple-energy technique, depending on clinical indications, electron arc therapy can be planned and delivered to allow either skin sparing or a uniform dose from the patient's surface to the desired treatment depth.
通过将不同电子能量的多个弧形束叠加到同一治疗表面,可实现电子弧形治疗所定义治疗体积内剂量均匀性的改善。每个弧形段和能量的相对权重由计算机优化确定,该优化可使整个治疗体积内的径向深度剂量变化最小化。除了6兆电子伏、9兆电子伏、12兆电子伏、16兆电子伏和20兆电子伏的标准电子束能量外,在使用6兆电子伏电子进行额外一次照射期间,通过在治疗表面添加填充物来创建一个新的电子弧形野。这个修正后的野在患者表面具有最大剂量且射程减小,可在剂量建成区补充标准电子弧形野所给予的剂量。通过使用这种多能量技术,根据临床指征,可规划并实施电子弧形治疗,以实现皮肤保护或从患者表面到所需治疗深度的均匀剂量。