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[肺泡复张手法对新生儿呼吸窘迫综合征患儿氧合的影响]

[Alveolar recruitment maneuvers oxygenation effects in newborns with infant respiratory distress syndrome].

作者信息

Aleksandrovich U S, Pechueva O A, Pshenisnov K V

出版信息

Anesteziol Reanimatol. 2013 Jan-Feb(1):21-5.

Abstract

UNLABELLED

Infant respiratory distress syndrome (IRDS) is a most common neonatal critical condition which is accompanied by the hypoxemia increase and needs the use of the highly invasive respiratory support methods. Alveolar recruitment maneuver is a one of the most promising and pathogenetically grounded method. The method is widely used in adults. but its use in Pediatric patients requires evidence of the effectiveness.

RESEARCH OBJECTIVE

To study alveolar recruitment maneuver use effectiveness in newborns with IRDS by the examining patient's clinical status and the nearest and long-term outcomes.

METHODS

Alveolar recruitment maneuver was used in 45 newborns with IRDS accompanied by the hypoxemia (group 1). Retrospective analysis of conditions and outcomes in 19 newborns with IRDS, without use of alveolar recruitment maneuver, was conducted in 2009 (group 2).

RESULTS

Alveolar recruitment maneuver improves ventilation and oxygenation in newborns with IRDS (paO2 53 torr in group 1 vs. 36 torr in group 2 and SpO2 95% vs. 90%). Alveolar recruitment maneuver use decreases the long term implications frequency in newborns with IRDS.

CONCLUSION

Alveolar recruitment maneuver is highly effective in newborns with IRDS. Its use decreases implications frequency and improves long term outcomes.

摘要

未标注

婴儿呼吸窘迫综合征(IRDS)是一种最常见的新生儿危急病症,伴有低氧血症增加,需要使用高侵入性呼吸支持方法。肺泡复张手法是最有前景且基于发病机制的方法之一。该方法在成人中广泛应用,但在儿科患者中的使用需要有效性证据。

研究目的

通过检查患者的临床状况以及近期和长期预后,研究肺泡复张手法在患有IRDS的新生儿中的使用效果。

方法

对45例伴有低氧血症的IRDS新生儿使用肺泡复张手法(第1组)。2009年对19例未使用肺泡复张手法的IRDS新生儿的病情和预后进行回顾性分析(第2组)。

结果

肺泡复张手法可改善患有IRDS的新生儿的通气和氧合(第1组动脉血氧分压为53托,第2组为36托;第1组脉搏血氧饱和度为95%,第2组为90%)。使用肺泡复张手法可降低患有IRDS的新生儿长期并发症的发生率。

结论

肺泡复张手法对患有IRDS的新生儿非常有效。其使用可降低并发症发生率并改善长期预后。

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