Department of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, China.
Am J Surg. 2013 Sep;206(3):314-9. doi: 10.1016/j.amjsurg.2012.10.044. Epub 2013 Jun 27.
The purpose of this study was to investigate the impact of subcarinal dissection on short-term outcomes and survival after esophagectomy in patients with thoracic esophageal squamous cell carcinoma.
Patients without subcarinal dissection were matched randomly to patients with subcarinal dissection in a 1:1 ratio according to 5 baseline variables (gender, pathologic stage, tumor location, histologic grade, and surgical approach) that may have major impacts on short-term outcomes and survival after esophagectomy in patients with thoracic esophageal squamous cell carcinoma. Preoperative clinical characteristics, short-term outcomes, and survival after esophagectomy of the 2 groups were compared.
There were 128 patients included in each group. Blood loss, postoperative pleural drainage volume, and the incidences of postoperative complications and pulmonary complications in the nondissection group were significantly less than in the dissection group. The comparison of overall survival curves and disease-free survival curves between the 2 groups showed no significant difference (P > .05).
Subcarinal dissection might be futile for patients with thoracic esophageal squamous cell carcinoma.
本研究旨在探讨隆突下解剖对胸段食管鳞癌患者食管癌切除术后短期结局和生存的影响。
根据可能对胸段食管鳞癌患者食管癌切除术后短期结局和生存有重大影响的 5 个基线变量(性别、病理分期、肿瘤位置、组织学分级和手术方式),将无隆突下解剖的患者与接受隆突下解剖的患者进行 1:1 随机匹配。比较两组患者的术前临床特征、食管癌切除术后短期结局和生存情况。
每组各纳入 128 例患者。非解剖组的术中出血量、术后胸腔引流量以及术后并发症和肺部并发症的发生率均明显少于解剖组。两组患者的总生存曲线和无病生存曲线比较,差异无统计学意义(P>.05)。
对于胸段食管鳞癌患者,隆突下解剖可能无益。