Itoh M, Hatazawa J, Miyazawa H, Matsui H, Meguro K, Yanai K, Kubota K, Watanuki S, Ido T, Matsuzawa T
Nuclear Medicine Division, Tohoku University, Sendai, Japan.
Gerontology. 1990;36(1):43-8. doi: 10.1159/000213174.
Cerebral blood flow and oxygen metabolism in aged normal subjects were measured with positron emission tomography and their relationship with brain atrophy was evaluated. Brain atrophy progressed in a linear fashion during aging while cerebral blood flow and oxygen metabolism were well preserved. The finding suggests that brain atrophy is an aging process less dependent on cerebral blood flow and metabolism over the course of normal aging.
采用正电子发射断层扫描技术测量了老年正常受试者的脑血流量和氧代谢,并评估了它们与脑萎缩的关系。在衰老过程中,脑萎缩呈线性进展,而脑血流量和氧代谢则保持良好。这一发现表明,在正常衰老过程中,脑萎缩是一个较少依赖脑血流量和代谢的衰老过程。