IEEE Trans Biomed Circuits Syst. 2010 Feb;4(1):27-38. doi: 10.1109/TBCAS.2009.2033035.
Pulse oximeters are ubiquitous in modern medicine to noninvasively measure the percentage of oxygenated hemoglobin in a patient's blood by comparing the transmission characteristics of red and infrared light-emitting diode light through the patient's finger with a photoreceptor. We present an analog single-chip pulse oximeter with 4.8-mW total power dissipation, which is an order of magnitude below our measurements on commercial implementations. The majority of this power reduction is due to the use of a novel logarithmic transimpedance amplifier with inherent contrast sensitivity, distributed amplification, unilateralization, and automatic loop gain control. The transimpedance amplifier, together with a photodiode current source, form a high-performance photoreceptor with characteristics similar to those found in nature, which allows LED power to be reduced. Therefore, our oximeter is well suited for portable medical applications, such as continuous home-care monitoring for elderly or chronic patients, emergency patient transport, remote soldier monitoring, and wireless medical sensing. Furthermore, our design obviates the need for an A-to-D and digital signal processor and leads to a small single-chip solution. We outline how extensions of our work could lead to submilliwatt oximeters.
脉搏血氧仪在现代医学中无处不在,通过比较红光和红外发光二极管光通过患者手指与光电探测器的传输特性,非侵入式地测量患者血液中含氧血红蛋白的百分比。我们提出了一种模拟的单片式脉搏血氧仪,总功耗为 4.8mW,比我们对商业实现的测量低一个数量级。这种功率降低的主要原因是使用了一种新颖的对数跨阻放大器,它具有固有对比度灵敏度、分布式放大、单边化和自动环路增益控制。跨阻放大器与光电二极管电流源一起形成了具有与自然界相似特性的高性能光电探测器,从而可以降低 LED 功率。因此,我们的血氧仪非常适合便携式医疗应用,例如老年或慢性患者的连续家庭护理监测、紧急病人运输、远程士兵监测和无线医疗传感。此外,我们的设计省去了 A/D 和数字信号处理器的需求,实现了小型的单芯片解决方案。我们概述了如何扩展我们的工作以实现亚毫瓦级的血氧仪。