Department of Otolaryngology/Head and Neck Surgery, St. Lucas Andreas Hospital, Jan Tooropstraat 164, 1061 AE, Amsterdam, The Netherlands,
Obes Surg. 2014 Jan;24(1):22-31. doi: 10.1007/s11695-013-1023-y.
Studies have reported significant improvement of obstructive sleep apnea (OSA) in obese patients after bariatric surgery (BS). Weight loss following BS is rapid in the first few months, but it can take at least 1 year to reach the final result. The aim of this study is to measure the effect of BS on various clinical, respiratory, and sleep parameters of OSA at two postoperative intervals.
Prospectively, all patients being evaluated for BS underwent a polysomnography (PSG). Patients diagnosed with OSA preoperatively were invited to undergo a PSG at least 6 months postoperatively and if OSA persisted, again at least 12 months postoperatively.
One hundred ten patients underwent a first postoperative PSG 7.7 months after surgery. The mean apnea-hypopnea index (AHI) significantly decreased from 39.5 to 15.6/h. In 58.2 %, the AHI was reduced to below 10 and in 25.5 % to below 5. Fifty patients underwent a first PSG 7.1 months and a second PSG 16.9 months after surgery. The mean AHI decreased from 49.1 to 22.7 to 17.4/h following BS.
BS initiates dramatic improvement and even remission of clinical and sleep parameters during the first 7 months, which continues at a slower rate over the next 10 months. We recommend a follow-up PSG after surgery to check for residual disease and if necessary retritration of continuous positive airway pressure, which may lead to higher treatment compliance.
研究报告称,肥胖患者接受减重手术后(BS)阻塞性睡眠呼吸暂停(OSA)有显著改善。BS 术后前几个月体重迅速下降,但至少需要 1 年才能达到最终结果。本研究旨在测量 BS 在两个术后间隔对 OSA 的各种临床、呼吸和睡眠参数的影响。
前瞻性地,所有接受 BS 评估的患者均接受多导睡眠图(PSG)检查。术前诊断为 OSA 的患者被邀请在术后至少 6 个月进行 PSG,如果 OSA 仍然存在,则在术后至少 12 个月进行 PSG。
110 例患者在手术后 7.7 个月进行了第一次术后 PSG。呼吸暂停低通气指数(AHI)从 39.5 显著降低到 15.6/h。58.2%的患者 AHI 降低到 10 以下,25.5%的患者 AHI 降低到 5 以下。50 例患者在手术后 7.1 个月和 16.9 个月进行了第一次 PSG。BS 后 AHI 从 49.1 降低到 22.7 到 17.4/h。
BS 在最初的 7 个月内引发了临床和睡眠参数的显著改善,甚至缓解,在接下来的 10 个月内以较慢的速度继续。我们建议术后进行随访 PSG 检查以检查残留疾病,如果需要,重新调整持续气道正压通气,这可能会提高治疗依从性。