Naysan Jonathan, Kodsi Sylvia R, Kristal Leonard
Department of Ophthalmology, North Shore-Long Island Jewish Health System, Great Neck, New York, USA.
J AAPOS. 2013 Aug;17(4):443-4. doi: 10.1016/j.jaapos.2013.04.002. Epub 2013 Jul 17.
Mastocytosis is a heterogeneous group of diseases characterized by the proliferation and abnormal infiltration of mast cells in tissue. These collections of mast cells are called mastocytomas. Solitary mastocytomas are cutaneous lesions, most commonly involving the extremities and trunk. Rubbing a cutaneous mastocytoma lesion leads to the release of histamine and other chemical mediators causing the lesion to become elevated and urticarial, similar to an allergic reaction. We describe a rare location of a presumed solitary mastocytoma of the lower eyelid in a young otherwise healthy child.
肥大细胞增多症是一组异质性疾病,其特征是肥大细胞在组织中增殖并异常浸润。这些肥大细胞聚集物称为肥大细胞瘤。孤立性肥大细胞瘤是皮肤病变,最常累及四肢和躯干。摩擦皮肤肥大细胞瘤病变会导致组胺和其他化学介质释放,使病变隆起并出现荨麻疹,类似于过敏反应。我们描述了一名健康幼儿下眼睑疑似孤立性肥大细胞瘤的罕见部位。