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眼肌麻痹患者的管理。

Managing the patient with oculomotor nerve palsy.

机构信息

Pediatric Ophthalmology and Ocular Genetics, Aravind Eye Care System, Madurai, Tamil Nadu, India.

出版信息

Curr Opin Ophthalmol. 2013 Sep;24(5):438-47. doi: 10.1097/ICU.0b013e3283645a9b.

Abstract

PURPOSE OF REVIEW

To provide clinically relevant information regarding the evaluation and current treatment options for oculomotor nerve palsies. We survey recent literature and provide some insights into these studies.

RECENT FINDINGS

Recent case reports highlight emerging new causes of oculomotor cranial nerve palsies, including sellar chordoma, odontogenic abscess, nonaneurysmal subarachnoid hemorrhage, polycythemia, sphenoiditis, neurobrucellosis, interpeduncular fossa lipoma, metastatic pancreatic cancer, leukemia, and lymphoma. Surgical studies have focused on modifications and innovations regarding strabismus surgery for this condition. New globe fixation procedures may include fixation to the medial orbital wall by precaruncular and retrocaruncular approaches, apically based orbital bone periosteal flap fixation and the suture/T-plate anchoring platform system.

SUMMARY

Management of oculomotor nerve palsy depends in part upon the underlying cause and anatomical location of the lesion. Careful clinical evaluation and appropriate imaging can identify a definitive cause in most cases. Surgical options depend on the number, extent, and severity of the muscles involved as well as the presence or absence of signs of aberrant regeneration. The clinician should also address issues that arise due to involvement of the pupil and accommodation. Strabismus surgery can be challenging but also rewarding with appropriate selection and staging of procedures.

摘要

目的综述

提供有关眼动神经麻痹评估和当前治疗选择的临床相关信息。我们调查了最近的文献,并对这些研究进行了一些分析。

最新发现

最近的病例报告强调了眼动颅神经麻痹的一些新的、新兴病因,包括鞍部脊索瘤、牙源性脓肿、非动脉瘤性蛛网膜下腔出血、红细胞增多症、蝶窦炎、神经布鲁氏菌病、脚间窝脂肪瘤、转移性胰腺癌、白血病和淋巴瘤。外科研究集中于斜视手术治疗这种疾病的改进和创新。新的眼球固定术可能包括经滑车前和滑车后入路固定在内侧眶壁、基于眶尖的骨骨膜瓣固定以及缝线/T 型板锚固平台系统。

总结

眼动神经麻痹的治疗部分取决于潜在病因和病变的解剖位置。仔细的临床评估和适当的影像学检查可以在大多数情况下确定明确的病因。手术选择取决于受累肌肉的数量、程度和严重程度,以及是否存在或不存在异常再生的迹象。临床医生还应解决因瞳孔和调节受累而引起的问题。斜视手术可能具有挑战性,但如果适当选择和分期手术,也会有回报。

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