18F-NaF PET/CT 意外检测到肺癌患者的脑转移。

Unexpected detection of brain metastases by 18F-NaF PET/CT in a patient with lung cancer.

机构信息

From the Department of Nuclear Medicine, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing, People's Republic of China.

出版信息

Clin Nucl Med. 2013 Nov;38(11):e429-32. doi: 10.1097/RLU.0b013e31828162ae.

DOI:10.1097/RLU.0b013e31828162ae

PMID:23877510

Abstract

In recent years, the inconsistent supply of (99m)Tc and the increasingly widespread use of PET/CT have led to a renewed interest in PET/CT bone scans using (18)F-NaF. Recently, a 64-year-old man with biopsy-proven lung cancer underwent an (18)F-NaF PET/CT bone scan due to a shortage of (99m)Tc. Unexpectedly, multiple nodular foci of increased tracer uptake were present in the brain, whereas there were no definitive bone metastases detected. Subsequently, brain MRI confirmed the presence of brain metastases.

摘要

近年来，由于 (99m)Tc 的供应不一致以及 PET/CT 的广泛应用，人们对使用 (18)F-NaF 的 PET/CT 骨扫描重新产生了兴趣。最近，一名 64 岁的肺癌活检证实患者由于 (99m)Tc 短缺而接受了 (18)F-NaF PET/CT 骨扫描。出乎意料的是，大脑中出现了多个结节状放射性摄取增加的灶，而没有发现明确的骨转移。随后，脑部 MRI 证实了脑转移的存在。