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Potassium channels, renal fibrosis, and diabetes.

作者信息

Menè Paolo, Pirozzi Nicola

机构信息

Department of Clinical and Molecular Medicine, Division of Nephrology, Sapienza University of Rome, Rome, Italy.

出版信息

Diabetes. 2013 Aug;62(8):2648-50. doi: 10.2337/db13-0603.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1939/3717840/cbe398e889ad/2648fig1.jpg

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本文引用的文献

1
Blockade of KCa3.1 ameliorates renal fibrosis through the TGF-β1/Smad pathway in diabetic mice.
Diabetes. 2013 Aug;62(8):2923-34. doi: 10.2337/db13-0135. Epub 2013 May 8.
2
Angiotensin II upregulates K(Ca)3.1 channels and stimulates cell proliferation in rat cardiac fibroblasts.
Biochem Pharmacol. 2013 May 15;85(10):1486-94. doi: 10.1016/j.bcp.2013.02.032. Epub 2013 Mar 7.
5
Diabetic nephropathy and extracellular matrix.
J Histochem Cytochem. 2012 Dec;60(12):976-86. doi: 10.1369/0022155412465073. Epub 2012 Oct 27.
6
Can we target tubular damage to prevent renal function decline in diabetes?
Semin Nephrol. 2012 Sep;32(5):452-62. doi: 10.1016/j.semnephrol.2012.07.008.
7
Advanced glycation end products promote proliferation of cardiac fibroblasts by upregulation of KCa3.1 channels.
Pflugers Arch. 2012 Dec;464(6):613-21. doi: 10.1007/s00424-012-1165-0. Epub 2012 Oct 2.
8
Potassium channels: the 'master switch' of renal fibrosis?
Nephrol Dial Transplant. 2010 Feb;25(2):353-5. doi: 10.1093/ndt/gfp634. Epub 2009 Nov 26.
9
Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels.
Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14518-23. doi: 10.1073/pnas.0903458106. Epub 2009 Aug 13.
10
Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition.
J Am Soc Nephrol. 2008 Dec;19(12):2282-7. doi: 10.1681/ASN.2008050513. Epub 2008 Nov 5.

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