Neurocentre Magendie, INSERM U 862 - Bordeaux University, F-33077 Bordeaux Cedex, France.
Neurosci Bull. 2013 Aug;29(4):467-76. doi: 10.1007/s12264-013-1363-6. Epub 2013 Jul 28.
Recovery of locomotor behavior following spinal cord injury can occur spontaneously in some vertebrates, such as fish, urodele amphibians, and certain reptiles. This review provides an overview of the current status of our knowledge on the anatomical and electrophysiological changes occurring within the spinal cord that lead to, or are associated with the re-expression of locomotion in spinally-transected salamanders. A better understanding of these processes will help to devise strategies for restoring locomotor function in mammals, including humans.
在一些脊椎动物中,如鱼类、有尾两栖类和某些爬行动物,脊髓损伤后的运动行为可以自发恢复。这篇综述概述了我们目前对脊髓内发生的解剖和电生理变化的认识,这些变化导致或与断脊髓的蝾螈重新表达运动有关。更好地理解这些过程将有助于制定策略来恢复包括人类在内的哺乳动物的运动功能。