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腹腔镜微创全胃切除术联合线性吻合器食管空肠吻合术——三十例经验总结。

Laparoscopic minimally invasive total gastrectomy with linear stapled oesophagojejunostomy--experience from the first thirty procedures.

机构信息

Department of Surgical Gastroenterology L, Aarhus University Hospital, Nørrebrogade 44, DK 8000 Åarhus C, Denmark.

出版信息

Anticancer Res. 2013 Aug;33(8):3269-73.

Abstract

BACKGROUND

There are only few reports on total gastrectomy by a laparoscopic surgical approach. One explanation is the fear of complications due to anastomotic dehiscence in oesophagojejunal anastomosis known to carry high morbidity and mortality. The introduction of staplers have contributed to making anastomosis safer and easier to perform and has facilitated more advanced laparoscopic surgery. In open surgery, most surgeons use a circular stapler for oesophagojejunal anastomosis or a hand sutured technique. Both techniques are difficult to use in laparoscopic surgery, especially if the oesophagus is narrow. To facilitate the creation of oesophagojejunal anastomoses, we have adopted a technique with a linear stapled anastomosis. Our method is based on a stapling technique where the oesophagus is divided above the gastric cardia followed by a oesophagojejunostomy performed with Covidien's new Endo GIA-60™ Ultra Universal stapler. The residual opening is closed with a 3-0 re-absorbable suture.

PATIENTS AND METHODS

From June 2009 to May 2012, 14 men and 16 women (median age=66 years, range=39-84 years) underwent laparoscopic total gastrectomy due to gastric cancer.

RESULTS

One patient died during hospital stay; corresponding to a postoperative mortality of 3,3%. Leakage in the oesophagojejunal anastomosis occurred in three patients (10%). Two of the patients with leakage in the oesophagojejunal anastomosis had an additional duodenal bulb leakage, which might have caused anastomotic dehiscence. The patients had a median postoperative hospital stay of six days (range=3-156 days). Six patients had a re-operation due to complications, including one endoscopic stent application in the anastomosis.

CONCLUSION

Even though a leakage rate of 10% can be considered high, this study describes a simple method for performing oesophagojejunostomy after gastrectomy by a laparoscopic approach independently of the width of the oesophagus. This study also shows that laparoscopic gastrectomy can be performed in more advanced stages of gastric cancer.

摘要

背景

仅有少数关于腹腔镜手术全胃切除术的报道。一种解释是由于食管胃吻合口的吻合口裂开,导致高发病率和死亡率,因此对吻合口并发症的担忧。吻合器的引入使得吻合更加安全、更容易进行,并促进了更先进的腹腔镜手术。在开放性手术中,大多数外科医生使用圆形吻合器进行食管胃吻合术或手工缝合技术。这两种技术在腹腔镜手术中都很难使用,尤其是在食管狭窄的情况下。为了方便食管胃吻合术的创建,我们采用了一种线性吻合技术。我们的方法是基于一种吻合技术,即在贲门上方将食管切开,然后使用柯惠公司的新 Endo GIA-60™Ultra 通用吻合器进行食管空肠吻合术。残余开口用 3-0 可吸收缝线关闭。

患者和方法

从 2009 年 6 月至 2012 年 5 月,14 名男性和 16 名女性(中位年龄=66 岁,范围=39-84 岁)因胃癌接受腹腔镜全胃切除术。

结果

1 名患者在住院期间死亡;术后死亡率为 3.3%。3 名患者(10%)发生食管胃吻合口漏。吻合口漏的 2 名患者另外发生十二指肠球部漏,可能导致吻合口裂开。患者的中位术后住院时间为 6 天(范围=3-156 天)。6 名患者因并发症再次手术,包括 1 例吻合口内镜支架应用。

结论

尽管漏率为 10%可能被认为较高,但本研究描述了一种简单的方法,可通过腹腔镜途径进行胃切除术后的食管空肠吻合术,而与食管的宽度无关。本研究还表明,腹腔镜胃切除术可以在胃癌的更晚期进行。

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