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儿童特发性椎间盘钙化:儿科病理学家眼中一种罕见疾病的非典型病例。

Idiopathic intervertebral disc calcification in childhood: an atypical case of an uncommon entity for pediatric pathologists.

作者信息

El Demellawy Dina, Robison Jacob G, Pollack Ian F, Green Michael D, Alper Cuneyt M, Reyes-Múgica Miguel

机构信息

1  Division of Pediatric Pathology, Children's Hospital of Pittsburgh of the University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.

出版信息

Pediatr Dev Pathol. 2013 Nov-Dec;16(6):432-7. doi: 10.2350/13-06-1343-CR.1. Epub 2013 Jul 31.

Abstract

Calcification of the intervertebral disc is a common occurrence in the adult population, but it is rare in children. However, its radiological and clinical findings are well described in the pediatric age group, with close to 150 publications on record. In contrast, little information is available regarding the histological features of this entity, which may prove to be challenging to surgical pathologists. Here we provide a detailed description of a young patient with an inflammatory retropharyngeal mass originating in a calcified intervertebral disc. A review of the pathological features described in the literature in English, with pathogenic considerations, is presented.

摘要

椎间盘钙化在成人中很常见,但在儿童中很少见。然而,其影像学和临床发现已在儿科年龄组中得到充分描述,有近150篇相关文献记录。相比之下,关于该实体组织学特征的信息很少,这可能给外科病理学家带来挑战。在此,我们详细描述了一名年轻患者,其炎性咽后肿块起源于钙化的椎间盘。并对英文文献中描述的病理特征及其致病因素进行了综述。

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