继发性正常压力脑积水患者分流手术预后的相关影响因素分析
Analysis of related factors affecting prognosis of shunt surgery in patients with secondary normal pressure hydrocephalus.
作者信息
Wang Cheng, Du Hang-gen, Yin Li-chun, He Min, Zhang Guo-jun, Tian Yong, Hao Bi-lie
机构信息
Department of Neurosurgery, Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310005, China.
出版信息
Chin J Traumatol. 2013;16(4):221-4.
OBJECTIVE
The management of secondary normal pressure hydrocephalus (sNPH) is controversial. Many factors may affect the surgery effect. The purpose of this study was to identify the possible factors influencing prognosis and provide theoretical basis for clinical treatment of sNPH.
METHODS
A retrospective study was carried out to investigate the results of 31 patients with sNPH who underwent ventriculoperitoneal shunt surgery from January 2007 to December 2011. We processed the potential influencing factors by univariate analysis and the result further by multivariate logistic regression analysis.
RESULTS
Factors including age, disease duration and Glasgow coma scale (GCS) score before surgery significantly influenced the prognosis of sNPH (P less than 0.05). Further logistic regression analysis showed that all the three factors are independent influencing factors.
CONCLUSION
Age, disease duration and GCS score before surgery have positive predictive value in estimating favorable response to surgical treatment for sNPH.
目的
继发性正常压力脑积水（sNPH）的治疗存在争议。许多因素可能影响手术效果。本研究旨在确定影响预后的可能因素，为sNPH的临床治疗提供理论依据。
方法
进行一项回顾性研究，调查2007年1月至2011年12月期间接受脑室腹腔分流术的31例sNPH患者的手术结果。我们通过单因素分析处理潜在影响因素，并通过多因素逻辑回归分析进一步分析结果。
结果
年龄、病程和术前格拉斯哥昏迷量表（GCS）评分等因素对sNPH的预后有显著影响（P<0.05）。进一步的逻辑回归分析表明，这三个因素均为独立影响因素。
结论
年龄、病程和术前GCS评分在评估sNPH手术治疗的良好反应方面具有阳性预测价值。
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