Koo Kyo Chul, Shim Geum Sook, Park Hyoun Hee, Rha Koon Ho, Choi Young Deuk, Chung Byung Ha, Hong Sung Joon, Lee Jae Woo
Department of Urology and Urological Science Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, South Korea.
J Forensic Leg Med. 2013 Aug;20(6):563-6. doi: 10.1016/j.jflm.2013.06.003. Epub 2013 Jul 4.
After the recent enactment of the chemical castration legislation for sex offenders in Korea, we sought to report primary treatment outcomes for 38 patients at the National Forensic Hospital since 2011. After chemical castration, these patients experienced reductions in frequency and intensity of sexual drive, frequency of masturbation and sexual fantasies. The incidence of adverse effects was similar to that of previous reports. Serial hormonal evaluations showed an association between testosterone level and degree of paraphilic and non-paraphilic sexual thoughts. A notable finding was an unexpected upsurge of testosterone levels with intense sexual drive and fantasy observed during the first 2 months after cessation of treatment. This suggested the need for a temporary anti-androgen therapy or close surveillance during this period. When proper precautions are taken, chemical castration may be an effective treatment strategy for paraphilic and non-paraphilic sex offenders.
在韩国近期针对性犯罪者颁布化学阉割立法后，我们试图报告自2011年以来国立法医医院38例患者的主要治疗结果。化学阉割后，这些患者的性冲动频率和强度、自慰频率及性幻想均有所降低。不良反应发生率与既往报告相似。系列激素评估显示睾酮水平与恋物癖及非恋物癖性想法的程度之间存在关联。一个显著发现是，在治疗停止后的头2个月内，观察到睾酮水平意外飙升，同时伴有强烈的性冲动和性幻想。这表明在此期间需要进行临时抗雄激素治疗或密切监测。若采取适当预防措施，化学阉割可能是治疗恋物癖及非恋物癖性犯罪者的有效治疗策略。
