Katikaneni Pavan K, Akkus Nuri I, Tandon Neeraj, Modi Kalgi
Department of Cardiology, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA 71103, USA.
J Invasive Cardiol. 2013 Aug;25(8):E163-6.
The incidence of cocaine-induced myocardial infarction (MI) in pregnancy is unknown. During the peripartum period, cocaine-abusing women are highly susceptible to MI caused by the effect of cocaine on a heart that is already stressed by hemodynamic changes of pregnancy. MI is an infrequent event during pregnancy and the peripartum period, with an estimated rate of 1 in 16,000 patients. Spontaneous coronary artery dissection (SCAD) can account for up to 27% of pregnancy-related MIs. We describe a case of MI diagnosed by increased troponin I levels in a postpartum patient with recent crack cocaine use in the setting of SCAD that required percutaneous coronary intervention of the left anterior descending and diagonal arteries. We also provide a comprehensive review of published literature related to this clinical entity.
孕期可卡因诱发心肌梗死（MI）的发生率尚不清楚。在围产期，滥用可卡因的女性极易发生心肌梗死，这是由于可卡因对已因孕期血流动力学变化而承受压力的心脏产生影响所致。心肌梗死在孕期和围产期是罕见事件，估计发生率为1/16000患者。自发性冠状动脉夹层（SCAD）可占与妊娠相关心肌梗死的27%。我们描述了一例产后患者，近期使用快克可卡因，在SCAD情况下肌钙蛋白I水平升高诊断为心肌梗死，该患者需要对左前降支和对角支动脉进行经皮冠状动脉介入治疗。我们还对与此临床实体相关的已发表文献进行了全面综述。
