Ponikvar Rafael
Department of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Ther Apher Dial. 2013 Aug;17(4):416-8. doi: 10.1111/1744-9987.12089.
The aim of our retrospective analysis with prospective collected data was to evaluate the patency of thigh expanded polytetrafluoroethylene (ePTFE) arteriovenous (AV) grafts, which were placed in chronic hemodialysis patients by the same interventional nephrologist skilled in hemodialysis access vascular surgery. From February 1991 until March 2013, 35 thigh ePTFE grafts were placed in 31 chronic hemodialysis patients. Twenty (57%) were women, mean age 58.7 ± 14.5, dialysis vintage 11.9 ± 7.3 years, mean number of previous vascular accesses 4.4 ± 1.9. Two of the 35 (5.7%) grafts were lost to follow-up, immediate failure occurred in 1/35 (2.8%) grafts, and thrombosis appeared within 30 days in 2/35 (5.7%) grafts. Four of the 31 patients died with functioning grafts, while in 9/31 patients the grafts are still patent. In the remaining 17 AV grafts that thrombosed, no surgical intervention was performed in 8/17, while 18 thrombectomies (two per graft) were performed in 9/17 to maintain graft patency. The immediate success rate was 97.1%. Primary patency was from 0-3251 days, on average 906 ± 898, median 472, cumulative patency (N = 33) was from 0-3251 days, on average 1174 ± 954, median 966. Cumulative patency of the grafts that were patent for more than 30 days (N = 30) was from 153-3251 days, on average 1298 ± 921, median 1207. The ePTFE graft survival after the 1st year was 78%, after the 2nd year 74%, after the 3rd year 66%, after the 4th year 56%, after the 5th year 52%, and after the 9th year 13 %. The longest patency was 3251 days without any intervention. Steal syndrome occurred in two patients after 2522 and 275 days after fistula placement.
我们对前瞻性收集的数据进行回顾性分析的目的是评估大腿部膨体聚四氟乙烯(ePTFE)动静脉(AV)移植物的通畅情况,这些移植物由同一位精通血液透析通路血管手术的介入肾脏病医生植入慢性血液透析患者体内。从1991年2月至2013年3月,31例慢性血液透析患者植入了35条大腿部ePTFE移植物。其中20例(57%)为女性,平均年龄58.7±14.5岁,透析龄11.9±7.3年,既往血管通路平均数量4.4±1.9个。35条移植物中有2条(5.7%)失访,1条移植物(2.8%)立即失败,2条移植物(5.7%)在30天内发生血栓形成。31例患者中有4例在移植物功能良好时死亡,9例患者的移植物仍保持通畅。在其余17条发生血栓形成的AV移植物中,17条中有8条未进行手术干预,17条中有9条进行了18次取栓术(每条移植物2次)以维持移植物通畅。即刻成功率为97.1%。初次通畅时间为0至3251天,平均906±898天,中位数472天,累积通畅时间(N = 33)为0至3251天,平均1174±954天,中位数966天。通畅超过30天的移植物(N = 30)的累积通畅时间为153至3251天,平均1298±921天,中位数1207天。第1年后ePTFE移植物存活率为78%,第2年后为74%,第3年后为66%,第4年后为56%,第5年后为52%,第9年后为13%。最长通畅时间为3251天,未进行任何干预。2例患者在造瘘术后2522天和275天发生窃血综合征。