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临床管理能否改善自残后的结果?来自英格兰自残多中心研究的结果。

Does clinical management improve outcomes following self-harm? Results from the multicentre study of self-harm in England.

机构信息

Centre for Mental Health and Risk, Centre for Suicide Prevention, University of Manchester, Manchester, United Kingdom.

出版信息

PLoS One. 2013 Aug 1;8(8):e70434. doi: 10.1371/journal.pone.0070434. Print 2013.

Abstract

BACKGROUND

Evidence to guide clinical management of self-harm is sparse, trials have recruited selected samples, and psychological treatments that are suggested in guidelines may not be available in routine practice.

AIMS

To examine how the management that patients receive in hospital relates to subsequent outcome.

METHODS

We identified episodes of self-harm presenting to three UK centres (Derby, Manchester, Oxford) over a 10 year period (2000 to 2009). We used established data collection systems to investigate the relationship between four aspects of management (psychosocial assessment, medical admission, psychiatric admission, referral for specialist mental health follow up) and repetition of self-harm within 12 months, adjusted for differences in baseline demographic and clinical characteristics.

RESULTS

35,938 individuals presented with self-harm during the study period. In two of the three centres, receiving a psychosocial assessment was associated with a 40% lower risk of repetition, Hazard Ratios (95% CIs): Centre A 0.99 (0.90-1.09); Centre B 0.59 (0.48-0.74); Centre C 0.59 (0.52-0.68). There was little indication that the apparent protective effects were mediated through referral and follow up arrangements. The association between psychosocial assessment and a reduced risk of repetition appeared to be least evident in those from the most deprived areas.

CONCLUSION

These findings add to the growing body of evidence that thorough assessment is central to the management of self-harm, but further work is needed to elucidate the possible mechanisms and explore the effects in different clinical subgroups.

摘要

背景

指导自我伤害临床管理的证据很少,试验招募了选择性样本,并且指南中建议的心理治疗方法在常规实践中可能无法获得。

目的

研究患者在医院接受的治疗与后续结果之间的关系。

方法

我们在十年期间(2000 年至 2009 年)确定了在英国三个中心(德比、曼彻斯特、牛津)就诊的自我伤害发作。我们使用既定的数据收集系统,研究管理的四个方面(心理社会评估、医疗入院、精神病入院、转介给专门的心理健康随访)与 12 个月内重复自我伤害之间的关系,同时调整了基线人口统计学和临床特征的差异。

结果

在研究期间,共有 35938 人因自我伤害就诊。在其中两个中心,接受心理社会评估与重复自我伤害的风险降低 40%相关,风险比(95%置信区间):中心 A 0.99(0.90-1.09);中心 B 0.59(0.48-0.74);中心 C 0.59(0.52-0.68)。几乎没有迹象表明,明显的保护作用是通过转介和随访安排介导的。心理社会评估与降低重复风险之间的关联在最贫困地区的人群中似乎最不明显。

结论

这些发现增加了越来越多的证据,即彻底评估是自我伤害管理的核心,但需要进一步工作来阐明可能的机制,并探讨不同临床亚组的效果。

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