用于靶向类风湿关节炎的自组装硫酸葡聚糖纳米粒子。
Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis.
机构信息
Department of Chemical Engineering, Kyung Hee University, Gyeonggi-do 449-701, Republic of Korea.
出版信息
Chem Commun (Camb). 2013 Nov 14;49(88):10349-51. doi: 10.1039/c3cc44260h.
PMID:23942894
Abstract
The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis.
摘要
该两亲嵌段共聚物由亲水性硫酸葡聚糖作为靶向配体和疏水性聚己内酯作为疏水段组成，通过点击化学制备自组装纳米粒子以靶向类风湿关节炎。
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