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异物嵌塞作为嗜酸性粒细胞性食管炎的表现。

Foreign body impaction as presentation of eosinophilic esophagitis.

机构信息

Division of Otolaryngology-Head and Neck Surgery, The University of Utah, Salt Lake City, Utah, USA.

出版信息

Otolaryngol Head Neck Surg. 2013 Nov;149(5):679-81. doi: 10.1177/0194599813500462. Epub 2013 Aug 19.

DOI:10.1177/0194599813500462
PMID:23959816
Abstract

Esophageal foreign body is a frequent pediatric presentation, and eosinophilic esophagitis (EoE) is an important underlying disease. To determine characteristics common in the presentation of esophageal foreign body indicative of underlying EoE and reach a recommendation for the appropriate scenario in which to obtain esophageal mucosal biopsy, 312 pediatric esophageal foreign bodies requiring operative removal were reviewed. Patients older than 18 years or with a known history of esophageal surgery or pathology were excluded. Eligibility criteria were met in 271 cases. Twenty-seven patients were biopsied, and 18 were diagnosed with EoE. The following factors were identified in the EoE population: food impaction (89%), older age (average 12.2 years), male sex (78%), atopic disease (61%), previous esophageal foreign body or frequent dysphagia (83%), and endoscopic abnormalities (100%). These factors are all associated with an underlying diagnosis of EoE, and patients meeting these criteria should be strongly considered for intraoperative esophageal mucosal biopsy.

摘要

食管异物是儿科常见的急症,嗜酸性食管炎(EoE)是一种重要的潜在疾病。为了确定食管异物表现出的与 EoE 相关的特征,并为获取食管黏膜活检的适当情况提出建议,我们回顾了 312 例需要手术取出的小儿食管异物。排除了年龄大于 18 岁或已知有食管手术或病理史的患者。符合条件的患者有 271 例,其中 27 例接受了活检,18 例诊断为 EoE。EoE 患者具有以下特征:食物嵌塞(89%)、年龄较大(平均 12.2 岁)、男性(78%)、特应性疾病(61%)、既往食管异物或频繁吞咽困难(83%)和内镜异常(100%)。这些因素均与潜在的 EoE 诊断相关,符合这些标准的患者应强烈考虑在术中进行食管黏膜活检。