Heathcote J Godfrey
Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Saudi J Ophthalmol. 2012 Apr;26(2):125-31. doi: 10.1016/j.sjopt.2012.02.008.
Transitional papilloma (inverted papilloma, Schneiderian papilloma) is a relatively common, benign epithelial neoplasm of the sinonasal tract that also occurs in the lacrimal drainage system. The name transitional papilloma is recommended because it reflects the key histological features required for pathological diagnosis, as well as the histogenesis of the tumour. The histogenesis of the tumour is reviewed, together with its natural history, which is characterized by bone remodelling and destruction, a tendency to recur and to undergo malignant transformation. Biomarkers associated with these features have been identified in the sinonasal tumours and may also be of relevance to the lacrimal sac tumours, although the necessary studies have not yet been undertaken.
移行性乳头状瘤（内翻性乳头状瘤、施耐德乳头状瘤）是鼻窦相对常见的良性上皮性肿瘤，也可发生于泪道系统。推荐使用移行性乳头状瘤这一名称，因为它反映了病理诊断所需的关键组织学特征以及肿瘤的组织发生。本文回顾了该肿瘤的组织发生及其自然史，其特点为骨质重塑和破坏、有复发及恶变倾向。鼻窦肿瘤中已鉴定出与这些特征相关的生物标志物，泪囊肿瘤可能也与之相关，不过尚未开展必要的研究。
