Division of Rehabilitation and Ageing, School of Community Health Sciences, University of Nottingham, Nottingham, UK.
Division of Rehabilitation and Ageing, School of Community Health Sciences, University of Nottingham, Nottingham, UK.
J Am Med Dir Assoc. 2014 Jan;15(1):8-16. doi: 10.1016/j.jamda.2013.06.012. Epub 2013 Aug 19.
To describe the prevalence of hypertension in care home residents, its treatment, change in treatment over time, and the achievement of blood pressure (BP) control.
The PubMed, Cochrane, Embase, and PsychINFO databases were searched for observational studies involving care home residents with a diagnosis of hypertension. The search was limited to English language articles involving adults and humans published from 1990 onward. Abstracts and titles were reviewed with eligible articles read in full. Bibliographies were examined for further relevant studies. The final selection of studies was then analyzed and appraised.
Sixteen articles were identified for analysis, of which half were studies carried out in the United States. The prevalence of hypertension in care home residents was 35% (range 16%-71%); 72% of these were on at least 1 antihypertensive (mean 1.5 antihypertensives per individual), with diuretics being the most common. The prevalence of hypertension in study populations was greater in more recent studies (P = .004). ACEi/ARBs (P = .001) and β-blockers (P = .04) were prescribed more frequently in recent studies, whereas use of calcium-channel blockers and diuretics remained unchanged over time. The number of antihypertensives prescribed per patient was higher (correlation 0.332, P = .009), whereas fewer patients achieved target BP (correlation -0.671, P = .099) in more recent studies.
Hypertension is common in care home residents and is commonly treated with antihypertensive drugs, which were prescribed more frequently in more recent studies but with no better BP control. These studies indicate a tendency toward increasing polypharmacy over time, with associated risk of adverse events, without demonstrable benefit in terms of BP control.
描述养老院居民高血压的患病率、治疗情况、随时间变化的治疗变化以及血压(BP)控制的达标情况。
检索 PubMed、Cochrane、Embase 和 PsychINFO 数据库,以获取涉及诊断为高血压的养老院居民的观察性研究。搜索仅限于 1990 年以后发表的、涉及成年人和人类的英文文章。审查摘要和标题,然后阅读符合条件的文章全文。检查参考文献以获取更多相关研究。最后对研究进行分析和评估。
确定了 16 篇文章进行分析,其中一半是在美国进行的研究。养老院居民高血压的患病率为 35%(范围 16%-71%);其中 72%的人至少使用 1 种降压药(平均每人使用 1.5 种降压药),最常见的是利尿剂。最近研究中研究人群的高血压患病率更高(P =.004)。ACEi/ARB(P =.001)和β受体阻滞剂(P =.04)在最近的研究中更常被开处方,而钙通道阻滞剂和利尿剂的使用随时间保持不变。每位患者开的降压药数量更高(相关性 0.332,P =.009),但最近的研究中达到目标 BP 的患者更少(相关性-0.671,P =.099)。
高血压在养老院居民中很常见,通常用降压药治疗,最近的研究中更常开这些药物,但血压控制没有改善。这些研究表明,随着时间的推移,药物联合使用呈增加趋势,同时存在不良事件的相关风险,但在血压控制方面没有明显获益。