Cain Rachel B, Zarka Matthew A, Hinni Michael L
Department of Otolaryngology - Head and Neck Surgery, Mayo Clinic, Phoenix, Arizona.
Head Neck. 2014 Apr;36(4):E39-43. doi: 10.1002/hed.23460. Epub 2013 Nov 18.
Hibernomas are rare, benign tumors of brown adipose tissue uncommonly found in the head and neck.
A review of the English-language literature was conducted for this study. We present a series of 2 laryngeal hibernomas treated with transoral laser microsurgical resection at a tertiary referral center over a period of 18 years.
Only 2 cases of laryngeal hibernoma have been previously described in the literature. Two additional cases were encountered at our institution. Preoperative imaging demonstrated a well-circumscribed neoplasm with fat density compatible with lipoma, but internal heterogeneity and vascularity seen in the context of liposarcoma. Transoral laser microsurgical resection was successfully performed in each case.
Despite unique radiographic features, hibernomas are difficult to distinguish from well-differentiated liposarcoma and lipoma variants without pathologic correlation. Complete surgical resection is indicated. In our experience, transoral laser microsurgical excision of laryngeal hibernomas is a safe, effective treatment modality with little associated morbidity.
冬眠瘤是一种罕见的棕色脂肪组织良性肿瘤,很少见于头颈部。
本研究对英文文献进行了回顾。我们报告了在一家三级转诊中心18年间经口激光显微手术切除的2例喉冬眠瘤病例。
此前文献中仅描述过2例喉冬眠瘤。我们机构又遇到了另外2例。术前影像学显示一个边界清晰的肿瘤,其脂肪密度与脂肪瘤相符,但在脂肪肉瘤的情况下可见内部异质性和血管。每例均成功进行了经口激光显微手术切除。
尽管有独特的影像学特征,但如果没有病理关联,冬眠瘤很难与高分化脂肪肉瘤和脂肪瘤变体区分开来。建议进行完整的手术切除。根据我们的经验,经口激光显微手术切除喉冬眠瘤是一种安全、有效的治疗方式,相关发病率很低。