Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Medicina (Kaunas). 2013;49(4):200-5.
Ventricular septal defect after myocardial infarction is a rare but often life-threatening mechanical complication. The keys of management are a prompt diagnosis of ventricular septal defect and an aggressive approach to stabilize patient's hemodynamics. Invasive monitoring, judicious use of inotropes and vasodilators, and an intra-aortic balloon pump are recommended for the optimal support of patient's hemodynamics. The best results are achieved if optimally medically managed patients survive at least 4 weeks before elective surgery necessary for scar formation in a friable infarcted tissue. We report a case of acute myocardial infarction complicated by the rupture of ventricular septum. Instead of attempting an immediate surgical closure of ventricular septal defect, the postponed surgery was successfully performed 3 weeks after the occurrence of ventricular septal defect. Preoperatively, clinical and hemodynamic conditions of the patient were maintained stable with the support of an intra-aortic balloon pump and inotropes.
心肌梗死后出现室间隔缺损是一种罕见但常危及生命的机械性并发症。管理的关键在于迅速诊断室间隔缺损,并积极稳定患者的血流动力学。建议进行有创监测、合理使用正性肌力药和血管扩张剂以及主动脉内球囊泵,以最佳支持患者的血流动力学。如果经过最佳药物治疗的患者至少存活 4 周,等待脆弱的梗死组织形成瘢痕后再进行择期手术,可获得最佳效果。我们报告了一例急性心肌梗死并发室间隔破裂的病例。在发生室间隔缺损后 3 周,我们选择了推迟手术,而不是立即进行手术关闭室间隔缺损。在手术前,通过主动脉内球囊泵和正性肌力药支持,患者的临床和血流动力学状况保持稳定。