Food Safety and Inspection Service, Office of Public Health Science, U.S. Department of Agriculture, Washington, DC 20250, USA.
J Food Prot. 2013 Sep;76(9):1597-607. doi: 10.4315/0362-028X.JFP-13-046.
The U.S. Department of Agriculture (USDA) Food Safety and Inspection Service (FSIS) examined whether levels of dioxin-like compounds (DLCs) measured in FSIS-regulated meat and poultry products indicate possible concern for U.S. public health based on usual and recommended consumption patterns of meat and poultry for the U.S. population. The FSIS estimated daily dietary exposures and compared them with the reference dose (RfD) established by the U.S. Environmental Protection Agency (EPA) for potential noncancer risks from 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), assuming that all measured DLCs were represented by the RfD (i.e., not just TCDD alone). The estimates indicate that a typical U.S. adult daily exposure of DLCs from FSIS-regulated products is below the EPA-established RfD. Only children consuming chronic average daily servings of meat or poultry products containing the highest measured levels of DLCs may exceed the RfD. If one follows the recommendations from the 2010 Dietary Guidelines for Americans, all expected exposures to DLCs from FSIS-regulated products are estimated to be well below the RfD.
美国农业部(USDA)食品安全检验局(FSIS)检测了在 FSIS 监管的肉类和家禽产品中检测到的二恶英类化合物(DLCs)水平,这些化合物是否表明美国公众健康可能存在担忧,这是基于美国人口对肉类和家禽的通常和推荐的消费模式。FSIS 估计了每日饮食暴露量,并将其与美国环境保护署(EPA)为 2,3,7,8-四氯二苯并对二恶英(TCDD)建立的参考剂量(RfD)进行了比较,假设所有测量的 DLCs 都由 RfD 表示(即,不仅仅是 TCDD 本身)。这些估计表明,FSIS 监管产品中 DLCs 的典型美国成年人每日暴露量低于 EPA 确定的 RfD。只有食用含有最高测量水平 DLCs 的肉类或家禽产品的儿童可能会超过 RfD。如果人们遵循 2010 年美国人饮食指南的建议,那么预计从 FSIS 监管产品中接触 DLCs 的所有暴露量都将远低于 RfD。