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如何处理感染性主动脉腔内移植物。

How to manage infected aortic endografts.

作者信息

Herdrich B J, Fairman R M

机构信息

Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Perlman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

出版信息

J Cardiovasc Surg (Torino). 2013 Oct;54(5):595-604.

Abstract

Aortic endografts have become the preferred treatment for aneurysms of the descending thoracic aorta and the infrarenal aorta. The prevalence of endograft infections is about 0.6%, and with the growing number of patients with aortic endografts, the number of patients with endograft infections has also increased. It is important for physicians who treat aneurysmal disease with endografting to understand the pathophysiology, work-up, and treatment options available. Currently, the mainstay of treatment is prolonged antibiotic therapy, explant of all prosthetic material, and reconstruction of the vasculature with either an in situ or extra-anatomic bypass. However, there is a growing experience of less invasive treatment strategies that can be used in patients who cannot withstand an operation of this magnitude.

摘要

主动脉腔内移植物已成为治疗胸降主动脉和肾下腹主动脉瘤的首选方法。腔内移植物感染的发生率约为0.6%,随着接受主动脉腔内移植物治疗的患者数量不断增加,腔内移植物感染患者的数量也在上升。对于采用腔内移植物治疗动脉瘤疾病的医生来说,了解其病理生理学、检查方法和可用的治疗选择非常重要。目前,主要的治疗方法是延长抗生素治疗时间、取出所有假体材料,以及通过原位或解剖外旁路进行血管重建。然而,对于无法耐受如此大规模手术的患者,越来越多的经验表明可以采用侵入性较小的治疗策略。

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