Zipper J, Wheeler R G, Angelo S, Adrian H
Int J Fertil. 1977;22(3):155-161.
Electrochemical effects within the uterus are being studied, particularly as they pertain to IUDs made in total or in part of metals. The intrauterine potential as measured with either metal or nonpolarizable salt electrodes is positive at the fundal with respect to the cervical end of the uterus. Placement of dissimilar metal electrodes within the uterus will induce voltage gradients that are roughly predictable from their cell potential in blood as an electrolyte. When copper and zinc electrodes are placed at opposite ends of the uterus, they induce voltage gradients that are typically greater than 100 mv per cm. External copper and zinc wires connected at one end, and with the other ends in contact with various positions on the skin of rats, were found to influence potential gradients within the uterus. When a length of zinc wire was wound around the upper portion of the stem of a small Cu-7 200 IUD, it took about 1 year from insertion for the zinc to disappear. When the zinc wire was wound around the lower portion of the stem, it disappeared in 1 month. The zinc reduced intrauterine corrosion of the copper and it was more effective at reducing copper corrosion when in the lower stem position.
子宫内的电化学效应正在被研究，尤其是与全部或部分由金属制成的宫内节育器相关的效应。用金属电极或非极化盐电极测量时，子宫底部相对于子宫宫颈端的宫内电位为正。在子宫内放置不同的金属电极会诱导电压梯度，根据它们在作为电解质的血液中的电池电位大致可以预测这些梯度。当铜电极和锌电极放置在子宫的相对两端时，它们诱导的电压梯度通常大于每厘米100毫伏。发现一端相连、另一端与大鼠皮肤不同部位接触的外部铜丝和锌丝会影响子宫内的电位梯度。当一段锌丝缠绕在小型Cu-7 200宫内节育器的杆的上部时，从插入起大约需要1年锌才会消失。当锌丝缠绕在杆的下部时，它在1个月内就消失了。锌减少了铜的宫内腐蚀，并且当处于杆的下部位置时，在减少铜腐蚀方面更有效。
