Esposito Marco, Worthington Helen V
Cochrane Oral Health Group, School of Dentistry, The University of Manchester, Coupland 3 Building, Oxford Road, Manchester, UK, M13 9PL.
Cochrane Database Syst Rev. 2013 Sep 5;2013(9):CD004151. doi: 10.1002/14651858.CD004151.pub3.
BACKGROUND: Dental implants are used for replacing missing teeth. Placing dental implants is limited by the presence of adequate bone volume permitting their anchorage. Several bone augmentation procedures have been developed to solve this problem. Zygomatic implants are long screw-shaped implants developed as a partial or complete alternative to bone augmentation procedures for the severely atrophic maxilla. One to three zygomatic implants can be inserted through the posterior alveolar crest passing through the maxillary sinus, or externally to it, to engage the body of the zygomatic bone. A couple of conventional dental implants may also be needed in the frontal region of the maxilla to stabilise the prosthesis. The potential main advantages of zygomatic implants could be that bone grafting may not be needed and a fixed prosthesis could be fitted sooner. Another specific indication for zygomatic implants could be maxillary reconstruction after maxillectomy in cancer patients. OBJECTIVES: To assess the effects of zygomatic implants with and without bone augmenting procedures in comparison with conventional dental implants in augmented bone for the rehabilitation with implant-supported prostheses of severely resorbed maxillae. SEARCH METHODS: We searched the following electronic databases: the Cochrane Oral Health Group's Trials Register (to 17 June 2013), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2013, Issue 5), MEDLINE via OVID (1946 to 17 June 2013) and EMBASE via OVID (1980 to 17 June 2013). Personal contacts and all known zygomatic implant manufacturers were contacted to identify unpublished trials. No restrictions were placed on the language or date of publication when searching the electronic databases. SELECTION CRITERIA: Randomised controlled trials (RCTs) including participants with severely resorbed maxillae, who could not be rehabilitated with conventional dental implants, treated with zygomatic implants with and without bone grafts versus participants treated with bone augmentation procedures and conventional dental implants, with a follow-up of at least one year in function. DATA COLLECTION AND ANALYSIS: Two review authors would have extracted data from eligible studies and assessed their risk of bias independently and in duplicate. The results of included studies were to be combined in meta-analyses using random-effects models where there were more than four studies, and fixed-effect models where there were less than four studies. We would have expressed the estimate of the intervention effect as mean difference for continuous outcomes and risk ratio for dichotomous outcomes, with 95% confidence intervals. Heterogeneity was to be investigated including both clinical and methodological factors. MAIN RESULTS: We did not identify any RCTs which were eligible for inclusion in this review. AUTHORS' CONCLUSIONS: There is a need for RCTs in this area to assess whether zygomatic implants offer some advantages over alternative bone augmentation techniques for treating atrophic maxillae.
背景:牙种植体用于替代缺失牙。牙种植体的植入受限于是否存在足够的骨量以实现其锚固。已开发出多种骨增量手术来解决这一问题。颧骨种植体是一种长螺旋形种植体,是针对严重萎缩的上颌骨作为骨增量手术的部分或完全替代方案而研发的。可通过后牙槽嵴穿过上颌窦或在上颌窦外部插入一至三颗颧骨种植体,以锚定颧骨体。在上颌前部区域可能还需要几颗传统牙种植体来稳定修复体。颧骨种植体的潜在主要优点可能是无需进行骨移植且可更快安装固定修复体。颧骨种植体的另一个特定适应证可能是癌症患者上颌骨切除术后的上颌骨重建。 目的:评估与传统牙种植体相比,使用或不使用骨增量手术的颧骨种植体在增量骨中用于严重吸收的上颌骨的种植体支持修复体康复的效果。 检索方法:我们检索了以下电子数据库:Cochrane口腔健康组试验注册库(至2013年6月17日)、Cochrane对照试验中心注册库(CENTRAL)(Cochrane图书馆2013年第5期)、通过OVID检索的MEDLINE(1946年至2013年6月17日)以及通过OVID检索的EMBASE(1980年至2013年6月17日)。通过个人联系以及与所有已知的颧骨种植体制造商联系以识别未发表的试验。检索电子数据库时对语言或出版日期没有限制。 选择标准:随机对照试验(RCT),纳入严重吸收的上颌骨患者,这些患者无法使用传统牙种植体进行修复,比较使用或不使用骨移植的颧骨种植体治疗与使用骨增量手术和传统牙种植体治疗的患者,功能随访至少一年。 数据收集与分析:两位综述作者将从符合条件的研究中提取数据,并独立且重复地评估其偏倚风险。纳入研究的结果将在荟萃分析中合并,若研究超过四项则使用随机效应模型,若研究少于四项则使用固定效应模型。我们将干预效果估计值表示为连续结局的平均差和二分结局的风险比,并给出95%置信区间。将调查异质性,包括临床和方法学因素。 主要结果:我们未识别出任何符合本综述纳入标准的RCT。 作者结论:该领域需要进行RCT,以评估颧骨种植体在治疗萎缩性上颌骨方面是否比其他骨增量技术具有某些优势。
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