下咽癌放化疗与手术治疗结果的评估
An evaluation of the results of chemoradiotherapy and surgical treatment for hypopharyngeal cancer.
作者信息
Demirci Uğur, Özmen Ömer Afşın, Demiröz Candan, Kasapoğlu Fikret, Coşkun Hamdi Hakan, Özkan Lütfi, Onart Selçuk
机构信息
Department of Otolaryngology, Rentıp Hospital, 16140 Nilüfer, Bursa, Turkey.
出版信息
Kulak Burun Bogaz Ihtis Derg. 2013 Sep-Oct;23(5):275-81. doi: 10.5606/kbbihtisas.2013.65477.
OBJECTIVES
This study aims to evaluate the efficacy chemoradiotherapy and surgical treatment in patients with hypopharyngeal cancer.
PATIENTS AND METHODS
Between January 2003 and July 2009, 48 patients (31 males, 17 females; mean age 55.5±13.4 years; range 29 to 84 years) who were diagnosed with hypopharyngeal cancer were retrospectively evaluated. The patients were assigned into surgery (n=17) and chemoradiotherapy (n=31) groups.
RESULTS
The overall survival of the patients with advanced disease in the surgery group was statistically higher than those in the chemoradiotherapy group. The recurrence rate of the patients was 35.3% in the surgery group, whereas it was 41.4% in the chemoradiotherapy group.
CONCLUSION
Our study results indicated that the survival rates were higher in the surgery group. On the other hand, chemoradiotherapy had the advantage of laryngeal preservation.
目的
本研究旨在评估下咽癌患者放化疗及手术治疗的疗效。
患者与方法
回顾性评估2003年1月至2009年7月间48例被诊断为下咽癌的患者（31例男性，17例女性；平均年龄55.5±13.4岁；年龄范围29至84岁）。患者被分为手术组（n = 17）和放化疗组（n = 31）。
结果
手术组晚期疾病患者的总生存率在统计学上高于放化疗组。手术组患者的复发率为35.3%，而放化疗组为41.4%。
结论
我们的研究结果表明手术组的生存率更高。另一方面，放化疗具有保留喉功能的优势。
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