Department of General, Digestive and Endocrine Surgery, Robert-Debré Hospital, 51092 Reims, France.
J Visc Surg. 2013 Nov;150(5):355-8. doi: 10.1016/j.jviscsurg.2013.07.003. Epub 2013 Sep 4.
Splenic metastases develop in less than 1% of all metastatic cancers, and typically occur in a setting of disseminated disease. When isolated splenic metastasis occurs, the patient may be a candidate for aggressive treatment consisting mainly of splenectomy as described in the literature. However, the increased incidence of post-operative morbidity and severe infection after splenectomy are well known. We report a case of splenic metastasis that developed from colorectal cancer and was treated by laparoscopic-guided radiofrequency ablation. We reviewed the few reported cases of splenic metastasis (from colorectal and other primary cancers) treated by thermal ablation using radiofrequency (RF) or microwave (MW) energy sources.
Many studies have proved that thermal ablation for benign splenic pathology is both feasible and safe with no sacrifice in efficacy. However only a few cases of MW or RF treatment of splenic secondary tumor have been described; no complications have been reported with this treatment in contrast to the 15 to 27% morbidity rate for splenectomy.
When treatment of splenic metastasis is proposed with curative intent, thermal ablation by RF or by MW seems to be a feasible and safe technique resulting in spleen conservation with a low morbidity rate. Because of these features, thermal ablation seems an ideal treatment modality to obliterate splenic metastasis and may be an indispensable tool in the armamentarium of modern splenic surgery.
脾脏转移发生在所有转移性癌症的不到 1%,通常发生在弥漫性疾病的背景下。当孤立的脾脏转移发生时,患者可能是主要通过文献中描述的脾切除术进行积极治疗的候选者。然而,众所周知,脾切除术后发病率增加和严重感染。我们报告了一例由结直肠癌引起的脾脏转移病例,采用腹腔镜引导射频消融治疗。我们回顾了少数几例使用射频(RF)或微波(MW)能量源热消融治疗脾脏转移(来自结直肠和其他原发性癌症)的报道病例。
许多研究已经证明,对于良性脾脏病变,热消融在不影响疗效的情况下是可行且安全的。然而,只有少数几例 MW 或 RF 治疗脾脏继发性肿瘤的病例被描述;与脾切除术后 15%至 27%的发病率相比,这种治疗没有报告并发症。
当提出以治愈为目的治疗脾脏转移时,RF 或 MW 的热消融似乎是一种可行且安全的技术,可保留脾脏,发病率低。由于这些特点,热消融似乎是一种理想的治疗方法,可以消除脾脏转移,并可能成为现代脾脏手术武器库中不可或缺的工具。