Department of Pediatrics, Vanderbilt University Medical Center, 2146 Belcourt Ave, Nashville, TN 37212, USA.
Contemp Clin Trials. 2013 Nov;36(2):436-49. doi: 10.1016/j.cct.2013.08.013. Epub 2013 Sep 5.
Growing Right Onto Wellness (GROW) is a randomized controlled trial that tests the efficacy of a family-centered, community-based, behavioral intervention to prevent childhood obesity among preschool-aged children. Focusing on parent-child pairs, GROW utilizes a multi-level framework, which accounts for macro (i.e., built-environment) and micro (i.e., genetics) level systems that contribute to the childhood obesity epidemic. Six hundred parent-child pairs will be randomized to a 3-year healthy lifestyle intervention or a 3-year school readiness program. Eligible children are enrolled between ages 3 and 5, are from minority communities, and are not obese. The principal site for the GROW intervention is local community recreation centers and libraries. The primary outcome is childhood body mass index (BMI) trajectory at the end of the three-year study period. In addition to other anthropometric measurements, mediators and moderators of growth are considered, including genetics, accelerometry, and diet recall. GROW is a staged intensity intervention, consisting of intensive, maintenance, and sustainability phases. Throughout the study, parents build skills in nutrition, physical activity, and parenting, concurrently forming new social networks. Participants are taught goal-setting, self-monitoring, and problem solving techniques to facilitate sustainable behavior change. The GROW curriculum uses low health literacy communication and social media to communicate key health messages. The control arm is administered to both control and intervention participants. By conducting this trial in public community centers, and by implementing a family-centered approach to sustainable healthy childhood growth, we aim to develop an exportable community-based intervention to address the expanding public health crisis of pediatric obesity.
“茁壮成长”(GROW)是一项随机对照试验,旨在测试一种以家庭为中心、以社区为基础的行为干预措施在预防学龄前儿童肥胖方面的效果。该试验聚焦于亲子对,采用多层次框架,考虑了导致儿童肥胖流行的宏观(即建筑环境)和微观(即遗传)系统。将 600 对亲子对随机分配到为期 3 年的健康生活方式干预组或 3 年的入学准备计划组。符合条件的儿童年龄在 3 至 5 岁之间,来自少数族裔社区,且不肥胖。GROW 干预的主要场所是当地社区娱乐中心和图书馆。主要结局指标是 3 年研究结束时儿童的体质量指数(BMI)轨迹。除了其他人体测量学测量指标外,还考虑了生长的中介和调节因素,包括遗传、加速度计和饮食回忆。GROW 是一种分阶段强化干预,包括强化、维持和可持续性阶段。在整个研究过程中,父母会逐渐掌握营养、身体活动和育儿方面的技能,同时形成新的社交网络。研究人员会向参与者传授目标设定、自我监测和解决问题的技巧,以促进可持续的行为改变。GROW 课程采用低健康素养沟通和社交媒体来传达关键健康信息。对照组和干预组都将接受对照组的干预。通过在公共社区中心开展这项试验,并采用以家庭为中心的方法促进儿童健康成长的可持续性,我们旨在开发一种可推广的基于社区的干预措施,以应对不断扩大的儿童肥胖公共卫生危机。