Motta C P, Zuniga M
Hansen's Disease Control, Rio de Janeiro State, Brazil.
Int J Lepr Other Mycobact Dis. 1990 Sep;58(3):453-61.
In an analysis of the trend of Hansen's disease in Brazil, the "incidence register" or "detection rate" per 100,000 was used. The operational data analyzed were presumed to be related to true incidence because of the time elapsed (38 and 19 years) and because of the large number of cases. The statistical method used was the exponential curve fit. From 1950 to 1987, there was an average annual decrease in the rate of 3% as indicated by the regression coefficient (slope), but from 1969 to 1987 an increase of 6% per year was observed. If this last trend is sustained, the detection rate in the year 2000 will be 35.03 per 100,000 or, in a population estimated as 190,000,000 inhabitants, 66,600 new cases. For comparison, in 1983 there were 18,759 new cases registered. The trend analysis for each of the Brazilian political-administrative areas (states and territories) is more accentuated in the Center-West and Northeast Macroregions, with a slope of 8% and 10%, respectively. In some states, such as Paraiba, Rio Grande do Norte, and Alagoas, there were astonishingly positive slopes of 20%, 18% and 17%, respectively. The distribution of the new cases by clinical forms during most of the period studied (1969-1987) confirms the overall trends observed. There was an increase in the detection rate of the tuberculoid form of 5% annually--compared to the lepromatous (combined with borderline) rate of 3% per year--and, also, the increase in the tuberculoid form was greatest in the Center-West and Northeast Macroregions.(ABSTRACT TRUNCATED AT 250 WORDS)
在一项对巴西麻风病趋势的分析中,采用了每10万人的“发病率登记”或“检出率”。由于所经历的时间(38年和19年)以及病例数量众多,所分析的运营数据被假定与真实发病率相关。所使用的统计方法是指数曲线拟合。从1950年到1987年,回归系数(斜率)表明发病率平均每年下降3%,但从1969年到1987年,观察到每年增长6%。如果最后这一趋势持续下去,2000年的检出率将为每10万人35.03例,或者在估计有1.9亿居民的人口中,有66600例新病例。相比之下,1983年登记的新病例有18759例。对巴西每个政治行政区域(州和领地)的趋势分析在中西部和东北部大区更为明显,斜率分别为8%和10%。在一些州,如帕拉伊巴州、北里奥格兰德州和阿拉戈斯州,分别有惊人的20%、18%和17%的正斜率。在所研究的大部分时期(1969 - 1987年),新病例按临床类型的分布证实了所观察到的总体趋势。结核样型的检出率每年增加5%,而瘤型(合并界线类)的检出率每年为3%,而且结核样型的增加在中西部和东北部大区最为显著。(摘要截短于250字)