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[周围神经疾病作为常见疾病]

[Peripheral nerve disorders as common diseases].

作者信息

Kuwabara Satoshi

机构信息

Department of Neurology, Graduate School of Medicine, Chiba University.

出版信息

Brain Nerve. 2013 Sep;65(9):1071-5.

Abstract

Peripheral neuropathy occurs as a component of several common and rare diseases. It is heterogeneous in cause, diverse in pathology, and varied in severity. The term peripheral neuropathy includes symmetric polyneuropathy, single and multiple mononeuropathy, and radiculopathy. The major disorders include diabetic neuropathy, alcoholic neuropathy, and carpal tunnel syndrome. The incidence of cancer chemotherapy-induced neuropathy has been increasing substantially. Although the estimated prevalence of all different peripheral neuropathies is considerably high, possibly affecting 10% of the entire population, there is no existing systematic epidemiological study on all the aspects of peripheral nerve disorders. Neurologists should contribute to both fundamental and symptomatic treatments of patients seen in other sections. The important symptomatic therapies include treatments for neuropathic pain and autonomic dysfunction. There is increasing role for neurologists in treating HIV-related and anti-HIV drug-induced neuropathy. More active collaboration with neurologists, oncologists, and general physicians is necessary to improve the quality of life in patients with peripheral nerve disorders.

摘要

周围神经病变是多种常见和罕见疾病的组成部分。其病因各异,病理多样,严重程度也各不相同。术语“周围神经病变”包括对称性多发性神经病、单发性和多发性单神经病以及神经根病。主要疾病包括糖尿病性神经病变、酒精性神经病变和腕管综合征。癌症化疗引起的神经病变的发生率一直在大幅上升。尽管所有不同类型周围神经病变的估计患病率相当高,可能影响整个人口的10%,但目前尚无关于周围神经疾病所有方面的系统流行病学研究。神经科医生应参与其他科室所见患者的基础治疗和对症治疗。重要的对症治疗包括对神经性疼痛和自主神经功能障碍的治疗。神经科医生在治疗与HIV相关和抗HIV药物引起的神经病变方面的作用越来越大。为了提高周围神经疾病患者的生活质量,神经科医生、肿瘤学家和普通内科医生之间需要更积极的合作。

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