Capeci Craig M, Turchiano Michael, Strauss Eric J, Youm Thomas
Bull Hosp Jt Dis (2013). 2013;71(1):60-7.
Chondral injury in the knee is a unique challenge to the orthopaedic surgeon. Given the high probability of progression to knee arthrosis, the treatment of symptomatic cartilage defects of the knee has become an important surgical intervention in young, active patients. The demand for an alternative to prosthetic resurfacing has driven the trend towards biologic resurfacing and joint preservation. Osteochondral allografts are composed of hyaline cartilage attached to subchondral bone and are suited for large osteochondral lesions. This allograft tissue must be harvested, processed, and stored appropriately to reduce the risks of graft failure and potential complications. With appropriate indications and surgical techniques, osteochondral allografts have been shown to have good long-term graft survival and patient outcomes.
膝关节软骨损伤对骨科医生来说是一项独特的挑战。鉴于发展为膝关节骨关节炎的可能性很高，对于有症状的膝关节软骨缺损的治疗已成为年轻、活跃患者的一项重要手术干预措施。对假体表面置换替代方案的需求推动了生物表面置换和关节保留的趋势。骨软骨异体移植由附着于软骨下骨的透明软骨组成，适用于大面积骨软骨损伤。这种异体移植组织必须进行适当的采集、处理和储存，以降低移植失败和潜在并发症的风险。在有适当的适应症和手术技术的情况下，骨软骨异体移植已被证明具有良好的长期移植存活率和患者预后。
