Chai Ying, Chen Minjie, Zhang Weijie, Zhang Wenhao
From the Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China.
J Craniofac Surg. 2013 Sep;24(5):1699-702. doi: 10.1097/SCS.0b013e3182801b64.
Microvascular decompression (MVD) has been the available method to cure trigeminal neuralgia (TN), and several factors have been discussed as significant predictors of excellent outcome after MVD.
This study aimed to find out the value of magnetic resonance tomographic angiography (MRTA) in predicting the outcome of MVD for TNs.
A total of 157 cases of TNs who underwent MVD have taken MRTA preoperatively and postoperatively and then were followed up for 5 years. The possible prognostic factors were analyzed by χ(2) test and Kaplan-Meier survival analysis.
Five years after MVD, 83.4% (131 cases) gave excellent, 10.2% (16 cases) gave good, and 6.4% (10 cases) gave poor results. A significant difference was found between the severity of postoperative neurovascular compression (χ(2) = 16.307, P < 0.01)/the relief rate of neurovascular compression (NVC) (χ(2) = 17.221, P < 0.01) and the outcome after MVD. However, no significant correlation was found between the severity of preoperative NVC and the outcome (χ(2) = 6.275, P = 0.329). The Kaplan-Meier survival curves showed that lower degree of postoperative NVC severity group and higher relief rate group had better pain relief after MVD.
Postoperative MRTA can help us predict the outcome of MVD; less severity of postoperative NVC and more relief of compression could be possible prognostic factors.
微血管减压术(MVD)一直是治疗三叉神经痛(TN)的有效方法,并且已经讨论了几个因素作为MVD术后良好预后的重要预测指标。
本研究旨在探讨磁共振断层血管造影(MRTA)在预测TN患者MVD手术预后中的价值。
157例接受MVD治疗的TN患者在术前和术后均进行了MRTA检查,并随访5年。通过χ²检验和Kaplan-Meier生存分析对可能的预后因素进行分析。
MVD术后5年,83.4%(131例)预后良好,10.2%(16例)预后较好,6.4%(10例)预后较差。术后神经血管压迫的严重程度(χ² = 16.307,P < 0.01)/神经血管压迫(NVC)的缓解率(χ² = 17.221,P < 0.01)与MVD术后的结果之间存在显著差异。然而,术前NVC的严重程度与预后之间未发现显著相关性(χ² = 6.275,P = 0.329)。Kaplan-Meier生存曲线显示,术后NVC严重程度较低组和缓解率较高组在MVD术后疼痛缓解情况较好。
术后MRTA有助于预测MVD的预后;术后NVC严重程度较低和压迫缓解程度较高可能是预后因素。