School of Rehabilitation Therapy, Queen's University, Kingston, ON, Canada.
Age Ageing. 2014 Jan;43(1):64-9. doi: 10.1093/ageing/aft135. Epub 2013 Sep 15.
to identify sensorimotor and psychosocial determinants of 3-year incident mobility disability.
prospective.
population-based sample of community-dwelling older persons.
community-living middle-aged and older persons (age: 50-85 years) without baseline mobility disability (n = 622).
mobility disability, defined as self-reported inability to walk a quarter mile without resting or inability to walk up a flight of stairs unsupported, was ascertained at baseline and 3-year follow-up. Potential baseline determinant characteristics included demographics, education, social support, financial condition, knee extensor strength, visual contrast sensitivity, cognition, depression, presence of chronic conditions and history of falls.
a total of 13.5% participant reported 3-year incident mobility disability. Age ≥75 years, female sex, knee extensor strength in the lowest quartile, visual contrast sensitivity <1.7 on the Pelli-Robson chart or significant depressive symptoms (CESD score >16) were independent determinants of 3-year incident mobility disability (ORs 1.84-16.51).
low visual contrast sensitivity, poor knee extensor strength and significant depressive symptoms are independent determinants of future onset of mobility disability.
确定 3 年内发生移动障碍的感觉运动和心理社会决定因素。
前瞻性。
基于人群的社区居住老年人样本。
无基线移动障碍的社区居住中年和老年人（年龄：50-85 岁）（n=622）。
移动障碍定义为自我报告无法不休息地行走四分之一英里或无法不支撑地走上一段楼梯，在基线和 3 年随访时确定。潜在的基线确定因素特征包括人口统计学、教育、社会支持、经济状况、膝关节伸肌力量、视觉对比敏感度、认知、抑郁、慢性疾病和跌倒史。
共有 13.5%的参与者报告了 3 年内发生的移动障碍。年龄≥75 岁、女性、膝关节伸肌力量处于最低四分位数、Pelli-Robson 图表上的视觉对比敏感度<1.7 或有明显抑郁症状（CESD 评分>16）是 3 年内发生移动障碍的独立决定因素（ORs 1.84-16.51）。
低视觉对比敏感度、膝关节伸肌力量差和明显的抑郁症状是未来移动障碍发病的独立决定因素。
