Protzel C, Hakenberg O W
Klinik und Poliklinik für Urologie, Universität Rostock, Rostock.
Aktuelle Urol. 2013 Sep;44(5):363-9. doi: 10.1055/s-0033-1354354. Epub 2013 Sep 16.
Due to the low incidence of penile cancer in Europe and North America and often decentralised patient management, data on the treatment of penile cancer are very rare. Nevertheless, recently relevant data have become available for the improvement of the therapy especially for the primary tumours. Penile conserving surgery is becoming more important for early tumour stages. The management of lymph nodes plays a key role for the successful treatment of patients with penile cancer. An invasive lymph node staging is recommended for all patients with primary pT1G2 or higher tumours. Neoadjuvant chemotherapy followed by salvage lymphadenectomy has shown promising results in patients with large and/or fixed inguinal lymph node metastases. Due to the results of recent studies, cisplatin/taxan-based chemotherapy regimens have to be recommended.
由于阴茎癌在欧洲和北美的发病率较低，且患者管理往往较为分散，关于阴茎癌治疗的数据非常罕见。然而，最近有了相关数据，这有助于改善治疗方法，尤其是针对原发性肿瘤的治疗。对于早期肿瘤阶段，保留阴茎的手术变得越来越重要。淋巴结的处理对于阴茎癌患者的成功治疗起着关键作用。对于所有原发性pT1G2或更高分期肿瘤的患者，建议进行有创性淋巴结分期。对于有大的和/或固定的腹股沟淋巴结转移的患者，新辅助化疗后行挽救性淋巴结清扫术已显示出有希望的结果。基于最近的研究结果，必须推荐以顺铂/紫杉烷为基础的化疗方案。
