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老年患者门诊腹腔镜胆囊切除术的安全性:利用 NSQIP 数据库分析 15248 例患者。

Safety of outpatient laparoscopic cholecystectomy in the elderly: analysis of 15,248 patients using the NSQIP database.

机构信息

Department of Surgery, Mount Sinai Medical Center, New York, NY.

出版信息

J Am Coll Surg. 2013 Dec;217(6):1038-43. doi: 10.1016/j.jamcollsurg.2013.08.001. Epub 2013 Sep 14.

Abstract

BACKGROUND

Studies have shown that laparoscopic cholecystectomy (LC) in an ambulatory setting is a safe alternative to the traditional overnight hospital stay. However, there are limited data on the morbidity and mortality of outpatient LC in elderly patients. We evaluated the safety of ambulatory LC in the elderly and identified risk factors that predict inpatient admission.

STUDY DESIGN

A retrospective analysis was performed using the American College of Surgeon's NSQIP database between 2007 and 2010. The database was searched for patients older than 65 years of age who underwent elective LC at all participating hospitals in the United States. Data from 15,248 patients were collected and we compared patients who underwent ambulatory procedures with those patients who were admitted for an inpatient stay.

RESULTS

Seven thousand four hundred and ninety-nine (48.9%) patients were ambulatory and 7,799 (51.1%) were nonambulatory. Postoperative complications included mortality (0.2% vs 1.5%; p < 0.001), stroke (0.1% vs 0.3%; p < 0.001), myocardial infarction (0.1% vs 0.6%; p < 0.001), pulmonary embolism (0.1% vs 0.3%; p = 0.005), and sepsis (0.2% vs 0.7%; p < 0.001) for ambulatory and nonambulatory cases, respectively. We identified significant independent predictors of inpatient admission and mortality, including congestive heart failure, American Society of Anesthesiologists class 4, bleeding disorder, and renal failure requiring dialysis.

CONCLUSIONS

We believe ambulatory LCs are safe in elderly patients as demonstrated by low complication rates. We identified multiple risk factors that might warrant inpatient hospital admission.

摘要

背景

研究表明,在门诊环境下进行腹腔镜胆囊切除术(LC)是传统过夜住院治疗的安全替代方案。然而,关于老年患者门诊 LC 的发病率和死亡率的数据有限。我们评估了老年人门诊 LC 的安全性,并确定了预测住院的危险因素。

研究设计

使用美国外科医师学院 NSQIP 数据库对 2007 年至 2010 年期间进行了回顾性分析。该数据库搜索了所有参与美国医院的年龄在 65 岁以上接受择期 LC 的患者。共收集了 15248 例患者的数据,我们比较了接受门诊手术的患者与住院治疗的患者。

结果

7499 例(48.9%)患者为门诊患者,7799 例(51.1%)为非门诊患者。术后并发症包括死亡率(0.2%比 1.5%;p<0.001)、中风(0.1%比 0.3%;p<0.001)、心肌梗死(0.1%比 0.6%;p<0.001)、肺栓塞(0.1%比 0.3%;p=0.005)和败血症(0.2%比 0.7%;p<0.001)。我们确定了导致住院和死亡的独立危险因素,包括充血性心力衰竭、美国麻醉医师协会 4 级、出血性疾病和需要透析的肾功能衰竭。

结论

我们认为,在老年患者中,门诊 LC 是安全的,并发症发生率较低。我们确定了多种可能需要住院治疗的危险因素。

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