A prominent role for triheteromeric GluN1/GluN2A/GluN2B NMDARs at central synapses.
作者信息
Soares Cary, Lee Kevin F H
机构信息
Neuroscience Graduate Program, Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada, K1H 8M5.
出版信息
J Neurosci. 2013 Sep 18;33(38):14975-7. doi: 10.1523/JNEUROSCI.3109-13.2013.
Abstract
摘要
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本文引用的文献
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Triheteromeric NMDA receptors at hippocampal synapses.三聚体 NMDA 受体在海马突触上。
J Neurosci. 2013 May 22;33(21):9150-60. doi: 10.1523/JNEUROSCI.0829-13.2013.
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NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease.NMDA 受体亚单位多样性：对受体特性、突触可塑性和疾病的影响。
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Synaptic NMDA receptors in basolateral amygdala principal neurons are triheteromeric proteins: physiological role of GluN2B subunits.外侧杏仁核主神经元中的突触 NMDA 受体是三聚体蛋白：GluN2B 亚基的生理作用。
J Neurophysiol. 2013 Mar;109(5):1391-402. doi: 10.1152/jn.00176.2012. Epub 2012 Dec 5.
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Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.在发育中的突触处，GluN2A 和 GluN2B 对 AMPA 受体的抑制作用存在明显差异：体内 NMDA 受体亚单位缺失的单细胞研究。
Neuron. 2011 Sep 22;71(6):1085-101. doi: 10.1016/j.neuron.2011.08.007. Epub 2011 Sep 21.
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Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses.三聚体 NR1/NR2A/NR2B 受体构成成年海马突触中主要的 N-甲基-D-天冬氨酸受体群体。
J Biol Chem. 2011 Mar 4;286(9):7558-66. doi: 10.1074/jbc.M110.182600. Epub 2010 Dec 29.
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Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle.第5层锥体神经元簇状树突中的突触整合：一个新的统一原则。
Science. 2009 Aug 7;325(5941):756-60. doi: 10.1126/science.1171958.
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A specialized NMDA receptor function in layer 5 recurrent microcircuitry of the adult rat prefrontal cortex.成年大鼠前额叶皮层第5层递归微回路中的一种特殊N-甲基-D-天冬氨酸受体功能。
Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16791-6. doi: 10.1073/pnas.0804318105. Epub 2008 Oct 15.
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NMDA receptor antagonists reveal age-dependent differences in the properties of visual cortical plasticity.NMDA受体拮抗剂揭示了视觉皮层可塑性特性中与年龄相关的差异。
J Neurophysiol. 2008 Oct;100(4):1936-48. doi: 10.1152/jn.90290.2008. Epub 2008 Jul 30.
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Rapid bidirectional switching of synaptic NMDA receptors.突触N-甲基-D-天冬氨酸受体的快速双向切换
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Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach.将N-甲基-D-天冬氨酸受体功能与受体亚基组成相关联：药理学方法的局限性。
J Neurosci. 2006 Feb 1;26(5):1331-3. doi: 10.1523/JNEUROSCI.5242-05.2006.
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