Agarwala S, Mitra D K
Department of Paediatric Surgery, All India Institute of Medical Science, New Delhi, India.
Pediatr Surg Int. 1996 Apr;11(4):266-8. doi: 10.1007/BF00178434. Epub 2013 Sep 21.
Fertility potential in patients with unilateral (UL) undescended testis is a debated topic. An experimental study was done in rats by surgically creating a UL undescended testis and studying its effect on their potential to father offspring when housed with female rats. No difference in fertility potential was observed in the various groups in this study. Since fertility was tested immediately after the rats became mature, it could be possible that fertility might decrease if the rats were tested in later adulthood. We conclude that experimentally created UL undescended testis does not cause damage sufficient to result in infertility in young adult rats. Also discussed is the significance of this finding in relation to UL undescended testis in humans.
单侧隐睾患者的生育潜能是一个存在争议的话题。通过手术制造单侧隐睾大鼠模型,并研究其与雌鼠合笼时对生育后代潜能的影响,进行了一项实验研究。本研究中各实验组的生育潜能未观察到差异。由于在大鼠成熟后立即进行生育能力测试,所以如果在成年后期进行测试,生育能力可能会下降。我们得出结论,实验制造的单侧隐睾不会对年轻成年大鼠造成足以导致不育的损害。还讨论了这一发现对于人类单侧隐睾的意义。