Zafar Saemah Nuzhat, Ahmad Saqib Qayyum, Zafar Nadeem
Department of Pediatric Ophthalmology and Strabismus, Al-Shifa Trust Eye Hospital, Rawalpindi 46000, Pakistan.
BMC Res Notes. 2013 Aug 1;6:304. doi: 10.1186/1756-0500-6-304.
Retinoblastoma is the most common pediatric ocular tumour. It may rarely present in adults. The present case adds to the number of 26 cases already published in literature since 1919 till 2013. Our aim is to highlight the rare occurrence of retinoblastoma in adults along with its features which differentiate it from paediatric retinoblastoma.
We describe a case of adult onset retinoblastoma (group E, according to the international classification of retinoblastoma) occurring in a 25 year old male. He presented with decreasing visual acuity in the right eye of 4 months duration. He had neo-vascular glaucoma and pseudohypopyon. B scan ultrsonography of his right eye showed intraocular growth without any calcification. The CT scan of the orbits and brain showed intraocular growth in the right eye with no calcification. Enucleation of the right eye was carried out. Retinoblastoma was confirmed on histopathology of the enuleated globe.
The present case adds to the number of adult Rb patients reported in literature. Early detection to salvage the life can be made possible if the clinician keeps a high index of suspicion when observing retinal mass of adult onset. Proper counselling of the patient in order to seek his full involvement in management may help in improving the prognosis of the disease.
视网膜母细胞瘤是最常见的儿童眼部肿瘤。它在成人中极为罕见。自1919年至2013年,本病例增加了文献中已发表的26例病例数量。我们的目的是强调视网膜母细胞瘤在成人中的罕见发生情况及其与儿童视网膜母细胞瘤不同的特征。
我们描述了一例发生在一名25岁男性身上的成人型视网膜母细胞瘤(根据视网膜母细胞瘤国际分类为E组)。他因右眼视力下降4个月前来就诊。他患有新生血管性青光眼和假性前房积脓。右眼的B超检查显示眼内有肿物但无钙化。眼眶和脑部的CT扫描显示右眼有眼内肿物且无钙化。遂对右眼进行了眼球摘除术。摘除眼球的组织病理学检查确诊为视网膜母细胞瘤。
本病例增加了文献中报道的成人视网膜母细胞瘤患者数量。如果临床医生在观察成人发生的视网膜肿物时保持高度怀疑,就有可能早期发现以挽救生命。对患者进行适当的咨询,使其充分参与治疗,可能有助于改善疾病的预后。