Kawakami S, Fukui I, Nagahama K, Sumi S, Takeuchi S, Oshima H
Department of Urology, Tokyo Medical and Dental University School of Medicine.
Nihon Hinyokika Gakkai Zasshi. 1990 Jan;81(1):130-3. doi: 10.5980/jpnjurol1989.81.130.
A 41-year-old miller undergoing hemodialysis for 9 years presented with recurrent episodes of asymptomatic gross hematuria of a 7 years' duration and left flank pain with slight fever of a four months' duration. CT scans revealed bilateral acquired cystic disease of the kidney (ACDK) and a mass (phi 4 cm) in the medial portion of the left kidney, which was angiographically a hypovascular tumor. Cystoscopic examination revealed multiple papillary tumors arising from the entire bladder wall. These findings suggested that the renal mass was a renal pelvic tumor. Bilateral nephroureterectomy with left paraaortic lymph nodes dissection and radical cystectomy were carried out, followed by urethrectomy two weeks later. Histologically, multiple papillary transitional cell carcinomas with G2 greater than G3 anaplasia were found in the left renal pelvis, the lower portion of the left ureter and the bladder. The tumors were predominantly superficial, although the renal pelvic one focally invaded into the muscular layer. Lymph node metastasis and renal cell carcinoma were not recognized. Postoperative course was uneventful with normal blood pressure, though anemia was slightly progressive. He has been free of disease for six months.
一名41岁的磨坊主,已接受9年血液透析治疗,出现持续7年的反复无症状肉眼血尿发作,以及持续4个月的左侧胁腹疼痛伴低热。CT扫描显示双侧获得性肾囊肿病(ACDK)以及左肾中部有一个肿块(直径4厘米),血管造影显示该肿块为少血管肿瘤。膀胱镜检查发现整个膀胱壁有多个乳头状肿瘤。这些发现提示肾脏肿块为肾盂肿瘤。遂进行双侧肾输尿管切除术并清扫左主动脉旁淋巴结,同时行根治性膀胱切除术,两周后行尿道切除术。组织学检查发现,左肾盂、左输尿管下段和膀胱有多个G2大于G3间变的乳头状移行细胞癌。肿瘤主要为浅表性,不过肾盂肿瘤有局部侵犯肌层。未发现淋巴结转移及肾细胞癌。术后过程平稳,血压正常,不过贫血稍有进展。他已无病生存6个月。