Dadras Farahnaz, Khoshjou Farhad
Urology and Nephrology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Iran J Kidney Dis. 2013 Sep;7(5):346-51.
Diabetic nephropathy is the leading cause of chronic kidney disease and end-stage renal disease. Oxidative stress has been recognized as a major contributor to its pathogenesis. Defensive mechanisms have also widely been studied. One of them, the NF-E2-Related Factor 2, is reviewed in this article.
糖尿病肾病是慢性肾脏病和终末期肾病的主要病因。氧化应激已被认为是其发病机制的主要促成因素。防御机制也得到了广泛研究。其中之一,即核因子E2相关因子2,将在本文中进行综述。